| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fumB | gcvP | azo2415 | azo1285 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.932 |
| fumB | gltB | azo2415 | azo3642 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.439 |
| fumB | nagAa | azo2415 | azo2517 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity. | 0.762 |
| fumB | paaZ | azo2415 | azo0299 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Conserved hypothetical dehydrogenase. Homology to paaZ of A. evansii of 83% (trembl|Q9F9V2). Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership. | 0.618 |
| gcvP | fumB | azo1285 | azo2415 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.932 |
| gcvP | gltB | azo1285 | azo3642 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.951 |
| gcvP | metH | azo1285 | azo3726 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
| gcvP | nagAa | azo1285 | azo2517 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity. | 0.643 |
| gcvP | paaZ | azo1285 | azo0299 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Conserved hypothetical dehydrogenase. Homology to paaZ of A. evansii of 83% (trembl|Q9F9V2). Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership. | 0.613 |
| gcvP | putA | azo1285 | azo3753 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.941 |
| gltB | fumB | azo3642 | azo2415 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.439 |
| gltB | gcvP | azo3642 | azo1285 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.951 |
| gltB | metH | azo3642 | azo3726 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.456 |
| gltB | nagAa | azo3642 | azo2517 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity. | 0.888 |
| gltB | paaH1 | azo3642 | azo0301 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable 3-hydroxybutyryl-CoA dehydrogenase; Activity:-3-acetoacetyl-CoA + NADPH = (S)-3-hydroxybutanoyl-CoA + NADP+ Entry name TREMBL:Q9F9V1 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR002110; ANK. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 2. PF02737; 3HCDH_N; 1. Identities = 344/510 (67%) Prediction: Signal peptide Signal peptide probability: 0.660 Number of predicted TMHs: 1; High confidence in function and specificity. | 0.441 |
| gltB | paaZ | azo3642 | azo0299 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Conserved hypothetical dehydrogenase. Homology to paaZ of A. evansii of 83% (trembl|Q9F9V2). Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership. | 0.837 |
| gltB | putA | azo3642 | azo3753 | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | Probable bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.942 |
| metH | gcvP | azo3726 | azo1285 | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.952 |
| metH | gltB | azo3726 | azo3642 | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.456 |
| metH | paaG1 | azo3726 | azo0300 | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Probable enoyl-CoA hydratase. Homology to paaG of E. coli of 60% (sprot|PAAG_ECOLI(SRS) COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Interpro: Enoyl-CoA hydratase/isomerase (IPR001753) Pfam: Enoyl-CoA hydratase/isomerase no signal peptide no TMHs; High confidence in function and specificity. | 0.551 |
