STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
naoA2-nitropropane dioxygenase; TREMBL:Q7MBF3: 80% identity, 89% similarity InterPro:IPR004136; 2nprop_dioxygen. IPR003009; FMN_enzyme. Pfam: PF03060; NPD tim: triosephosphate isomerase Non-secretory protein with no signal peptide. TMHMM predicted no transmembrane helices.; High confidence in function and specificity. (414 aa)    
Predicted Functional Partners:
narK
Probable nitrate transporters are involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. NarK is polytopic membrane protein with 12 transmembrane domains which is involved in nitrate uptake and nitrite excretion and is thought to function as a nitrate/nitrite antiporter. At low concentrations of nitrate, NarK mediates the electrogenic excretion of nitrite rather than nitrate/nitrite exchange., 90% similarity to a probable nitrate transporter protein in Azoarcus sp. EbN1., InterPRo:04737: nitrate transporter,Signal peptide no present, TMHx:12, ; High confid [...]
    
 0.866
ncd2-2
2-nitropropane dioxygenase precursor (EC 1.13.11.32) (Nitroalkane oxidase) (2-NPD). SPROT:Q01284: 28% identity, 44% similarity CATALYZES THE OXIDATION OF NITROALKANES TO PRODUCE THE CORRESPONDING CARBONYL COMPOUNDS. IT ACTS ON 2-NITROPROPANE BETTER THAN ON NITROETHANE AND 1-NITROPROPANE AND ANIONIC FORMS OF NITROALKANES ARE MUCH BETTER SUBSTRATES THAN ARE NEUTRAL FORMS. InterPro: 2-nitropropane dioxygenase InterPro; IPR004136; 2nprop_dioxygen. InterPro; IPR003009; FMN_enzyme. Pfam; PF03060; NPD thiE: thiamine-phosphate pyrophosphoryl Non-secretory protein with signal peptide probabilit [...]
  
  
 0.837
acpP
AcpP protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.786
nasA
Probable Nitrate reductase. Homology to nasA of K. oxytoca of 41% (sprot|NASA_KLEOX). Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants fungi and bacteria. InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain no signal peptide no TMH Helixturnhelix motif; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
     
  0.773
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.699
fabD
Probable malonyl CoA-acyl carrier protein transacylase. Homology to fabD of E. coli of 54% (sprot|FABD_ECOLI). Is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein. InterPro: Acyl transferase domain (IPR001227); Manyl CoA-acyl carrier protein transaylase (IPR004410) Pfam: Acyl transferase domain Tigrfam: fabD: malonyl CoA-acyl carrier protein no signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.659
cutA1
Periplasmic divalent cation tolerance protein .36% similarity to E.coli CutA1 protein involved in copper tolerance. InterPro:IPR004323; CutA1. Pfam:PF03091; CutA1; 1; High confidence in function and specificity.
       0.636
azo0259
Conserved hypothetical protein. Homology to xac 4098 of X. axonapodis of 36% (trembl|Q8PF87). No domains predicted. No signal peptide. No TMHs.
 
 
 0.603
napB1
Probable diheme cytochrome C; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
     
  0.586
napA1
Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
     
  0.586
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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