Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0334Conserved hypothetical secreted protein. Homology to BPP2140 of Bordetella parapertussis 0f 44% (trembl|Q7W8J3(SRS)) No domains predicted. Signal peptide present. No TMH present. 6PTHBS: 6-pyruvoyl tetrahydrobiopterin; Conserved hypothetical protein. (192 aa)    
Predicted Functional Partners:
azo1795
Conserved hypothetical protein; DNA topoisomerase I (EC 5.99.1.2). The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. cbiB: cobalamin biosynthesis protein; Specificity unclear.
 
    0.650
treZ
Malto-oligosyltrehalose trehalohydrolase(MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase).Involved in the trehalose biosynthesis,hydrolysing alpha-(1->4)-d-glucosidic linkage in 4-alpha-d-{(1->4)-alpha-d-glucanosyl}(n) trehalose to yield trehalose and alpha-(1->4)-d-glucan. 42% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.PF02922; isoamylase_N; 1; Specificity unclear.
  
    0.650
glgX
Putative glycogen debranching enzyme; Glycogen operon protein GlgX homolog.Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen. 46% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.F02922; isoamylase_N; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
  
  
 0.597
treS
Trehalose synthase(Maltose alpha-D-glucosyltransferase).Catalyzes the conversion of maltose into alpha,alpha- trehalose by transglucosylation. 54% Alp_amyl_cat_sub.IPR006047; Alpha_amyl_cat.InterPro: Glycoside hydrolase family 13. Pfam:PF00128; alpha-amylase; 1; High confidence in function and specificity.
  
    0.553
azo1803
Conserved hypothetical glycosyltransferase. Homology to ebA6914 of Azoarcus sp. EbN1 of 72% (gnl|keqq|eba:ebA6914(KEGG)). Pfam: Glycos_transf_1. Interpro: Glycosyl transferase, group 1. Proteins containign this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis,lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid. No signal peptide. No TM [...]
  
     0.532
glgA
Putative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
  
 0.494
azo1741
Putative DNA-ligase like protein Rv0938/MT0965. dnl1: DNA ligase I ATP-dependent; Specificity unclear; ORF4.
 
    0.487
azo1732
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Family membership.
  
     0.482
azo1737
Conserved hypothetical membrane protein. Homology to ebA6987 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA6987(KEGG)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein.
  
     0.460
azo1799
The first part of the protein (2202 bases) is 37% Glyco_hydro_77. Pfam:PF02446; 4A_glucanotrans; 1.TIGRFAMs:TIGR00217; malQ; 1. GO:5975/4134. The second part of the protein (from the base 2128 to the end) is 39%; Function unclear; ORF5.
  
    0.435
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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