STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parA2Probable ParA family protein; Sporulation initiation inhibitor protein soj. INHIBITS THE INITIATION OF SPORULATION SPO0J ANTAGONIZES THIS INHIBITION. SOJ ULTIMATELY INHIBITS THE ACTIVATION (PHOSPHORYLATION) OF SPO0A. IT IS NOT REQUIRED FOR CHROMOSOME PARTITIONING. InterPro: ParA family ATPase; Function unclear. (220 aa)    
Predicted Functional Partners:
parB
Probable chromosome partitioning protein,; High confidence in function and specificity; Belongs to the ParB family.
 
 
 0.959
azo0344
Probable Hypothetical Protein. No domains,features,motifs, or signal peptide present.
       0.797
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
 
 
 0.613
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.534
nhoA
N-hydroxyarylamine O-acetyltransferase; Belongs to the arylamine n-acetyltransferase family. Arylamine N-acetyltransferase is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Similar to TREMBL:Q98D42 (47% identity); TREMBL:Q8FHI6 (39% identity); SWISSPROT:P77567 (39% identity). InterPro (IPR001447): N-acetyltransferase Pfam (PF00797): N-acetyltransferase; High confidence in function and specificity.
       0.528
irgA1
Putative TonB-dependent receptor; 23% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1; High confidence in function and specificity.
    
   0.526
azo2400
Putative TonB outer membrane receptor protein.31% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; Function unclear.
    
   0.526
azo3555
TonB-dependent receptor, putative; COBALAMIN RECEPTOR PROTEIN; Specificity unclear.
    
   0.526
azo3556
Putative outer membrane TonB-dependent receptor,probably involved in iron metabolism. 20% Similar to the IrgA enterobactine outer membrane receptor in V. cholerae. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC VIBRIOBACTIN AN IRON CHELATIN SIDEROPHORE THAT ALLOWS V.CHOLERAE TO EXTRACT IRON FROM THE ENVIRONMENT. SWISSPROT:IRGA_VIBCH:P27772. 21% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1; Specificity unclear.
    
   0.526
irgA2
Putative TonB-dependent receptor; 24% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; High confidence in function and specificity.
    
   0.526
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.