Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
azo0350Conserved hypothetical secreted protein. Homology to gll2146 of G. violaceus of 44% (trembl|Q7NIN7(SRS)) no domains predicted signal peptide no TMHs; Conserved hypothetical protein. (431 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
  0.702
azo1483
Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...]
  
  
 0.656
nodJ
ABC transporter permease NodJ; Forms with NodI a membrane transport complex involved in the nodulation process. it probably exports a modified beta-1,4-linked n-acetylglucosamine oligosaccharide. Belongs to the ABC-2 integral membrane protein family, TREMBL:Q7WHD1 (49% identity); SWISSPROT:O52619 (49% identity). InterPro (IPR000412): ABC transporter, family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting six transmembrane helices. TC (3.A.1.102): The Lipooligosaccharide Exporter (LOSE) Family; High confidence in function and specificity.
       0.499
cpdA
Probable phosphodiesterase; Serine/threonine (S/T) phosphatases catalyse the dephosphorylation of phosphoserine and phosphothreonine residues. In mammalian tissues four different types of PP have been identified and are known as PP1, PP2A, PP2B and PP2C. Except for PP2C, these enzymes are evolutionary related. The catalytic regions of the proteins are well conserved TREMBL:Q7VZQ9: 41% identity, 50% similarity InterPro:IPR004843; M-ppestrase. Pfam:PF00149; Metallophos InterPro: Serine/threonine specific protein phosphatase No transmembrane helices sbcd: exonuclease SbcD; High confidence [...]
 
  
  0.458
azo3855
Alkaline phosphatase (EC 3.1.3.1) (ALP)is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH.It is found in nearly all living organisms,with the exception of some plants. 30% Alk_phosphtse.Alkaline phosphatase family Pfam:PF00245; alk_phosphatase; 1. Signal peptide present; High confidence in function and specificity.
     
 0.436
azo0352
Conserved hypothetical protein. Homology to mvpT of E. carotovora of 44% (trembl:Q6D393) No domains predicted. No TMHs No signal peptide.
       0.432
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.426
surE
Phosphoric-monoester phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.424
pyrF
Orotidine-5'-phosphate decarboxylase (Orotidylic decarboxylase) (OMP decarboxylase) (OMPdcase) (Uridine 5'-monophosphate synthase) (UMP synthase); High confidence in function and specificity; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
  0.421
add
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
     
  0.420
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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