STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0354Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (326 aa)    
Predicted Functional Partners:
azo3595
Hypothetical protein predicted by Glimmer/Critica.
  
  
 0.611
vsr
Putative hypothetical very short patch repair endonuclease. Homology to vrs of E. coli of 29% (sprot|VSR_ECOLI) All proteins in this family for which functions are known are G:T mismatch endonucleases that function in a specialized mismatch repair process used usually to repair G:T mismatches in specific sections of the genome. Interpro: DNA mismatch endonuclease vsr (IPR004603) Pfam: DNA mismatch endonuclease Vsr Tigrfam: vsr: DNA mismatch endonuclease no signal peptide no TMHs; Family membership.
 
   
 0.574
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.533
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.500
azo0771
Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase.
  
     0.497
azo0358
Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases).
 
     0.468
azo3757
Modification methylase TaqI (EC 2.1.1.72) (Adenine-specific methyltransferase TaqI) (M.TaqI). THIS METHYLASE RECOGNIZES THE DOUBLE-STRANDED SEQUENCE TCGA CAUSES SPECIFIC METHYLATION ON A-4 ON BOTH STRANDS AND PROTECTS THE DNA FROM CLEAVAGE BY THE TAQI ENDONUCLEASE. InterPro: N6 adenine-specific DNA methyltransferase N12 class; Family membership.
    
 0.443
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
 0.439
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
    
  0.429
acyH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.428
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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