| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acyH | amn | azo0587 | azo0116 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.590 |
| acyH | azo0354 | azo0587 | azo0354 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.431 |
| acyH | azo0771 | azo0587 | azo0771 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase. | 0.431 |
| acyH | azo3595 | azo0587 | azo3595 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Hypothetical protein predicted by Glimmer/Critica. | 0.696 |
| acyH | ksgA | azo0587 | azo2884 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.477 |
| acyH | metK | azo0587 | azo0589 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.851 |
| amn | acyH | azo0116 | azo0587 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.590 |
| amn | azo0354 | azo0116 | azo0354 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.425 |
| amn | azo0771 | azo0116 | azo0771 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase. | 0.425 |
| amn | azo3595 | azo0116 | azo3595 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Hypothetical protein predicted by Glimmer/Critica. | 0.726 |
| amn | ksgA | azo0116 | azo2884 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.597 |
| amn | metK | azo0116 | azo0589 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.510 |
| azo0203 | azo0354 | azo0203 | azo0354 | Conserved hypothetical membrane protein; TREMBL:Q82XH5: 33% identity, 44% similarity InterPro:IPR007404; DUF457. Pfam: PF04307; DUF457 fnt: formate/nitrite transporter Non-secretory protein with signal peptide probability of 0.391 TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein. | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.513 |
| azo0203 | azo0771 | azo0203 | azo0771 | Conserved hypothetical membrane protein; TREMBL:Q82XH5: 33% identity, 44% similarity InterPro:IPR007404; DUF457. Pfam: PF04307; DUF457 fnt: formate/nitrite transporter Non-secretory protein with signal peptide probability of 0.391 TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein. | Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase. | 0.513 |
| azo0354 | acyH | azo0354 | azo0587 | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.431 |
| azo0354 | amn | azo0354 | azo0116 | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.425 |
| azo0354 | azo0203 | azo0354 | azo0203 | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Conserved hypothetical membrane protein; TREMBL:Q82XH5: 33% identity, 44% similarity InterPro:IPR007404; DUF457. Pfam: PF04307; DUF457 fnt: formate/nitrite transporter Non-secretory protein with signal peptide probability of 0.391 TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein. | 0.513 |
| azo0354 | azo0358 | azo0354 | azo0358 | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases). | 0.482 |
| azo0354 | azo0771 | azo0354 | azo0771 | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase. | 0.497 |
| azo0354 | azo1876 | azo0354 | azo1876 | Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.425 |