STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0355Conserved hypothetical protein. Homology to lpg1234 of L.pneumophila of 42% (gnl|keqq|lpn:lpg1234(KEGG)). Has PF04471, Restriction endonuclease;IPR007560, Mrr_cat; Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. No TMHs. No signal peptide. (388 aa)    
Predicted Functional Partners:
vsr
Putative hypothetical very short patch repair endonuclease. Homology to vrs of E. coli of 29% (sprot|VSR_ECOLI) All proteins in this family for which functions are known are G:T mismatch endonucleases that function in a specialized mismatch repair process used usually to repair G:T mismatches in specific sections of the genome. Interpro: DNA mismatch endonuclease vsr (IPR004603) Pfam: DNA mismatch endonuclease Vsr Tigrfam: vsr: DNA mismatch endonuclease no signal peptide no TMHs; Family membership.
     
 0.788
azo0357
Hypothetical protein.
       0.572
azo0358
Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases).
       0.567
padC
Conserved hypothetical phenylacetyl-CoA:acceptor oxidoreductase. Homology to padC of A. evansiin of 61% (trembl|Q8L3B5). Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes (By similarity). Pfam: 4Fe-4S binding domain. Tigrfam: napF: ferredoxin-type protein NapF. no signal peptide. no TMHs; Family membership.
   
    0.520
azo2931
Conserved hypothetical protein. Homology to gsu0911 of G. sulfurreducens of 38% (tremblnew|AAR34238). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs.
   
    0.520
fdhB
Probable formate dehydrogenase iron-sulfur subunit. Homology to fdhB of W. succinogenes of 63% (SWISSPROT:FDHB_WOLSU) THIS CHAIN IS AN ELECTRON TRANSFER UNIT CONTAINING 18 CYSTEINE RESIDUES 16 OF WHICH OCCUR IN THREE CLUSTERS. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450); 7Fe ferredoxin (IPR000813); 3Fe-4S ferredoxin (IPR001080) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; High confidence in function and specificity.
   
    0.520
napG
Probable ferredoxin-type protein napG. Homology to napG of E. coli of 57% (sprot|NAPG_ECOLI). Involved in electron transfer in a wide variety of metabolic reactions. InterPro: MauM/NapG family ferredoxin-type protein (IPR004494); 7 Fe ferredoxin (IPR000813); 4Fe-4S ferredoxin; iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain Tigrfam: mauM_napG: MauM/NapG family ferredoxin-type protein no signal peptide no TMHs; High confidence in function and specificity.
   
    0.520
hsdM
Site-specific DNA-methyltransferase (adenine-specific); METHYLATION OF SPECIFIC ADENINE RESIDUES; REQUIRED FOR BOTH RESTRICTION AND MODIFICATION ACTIVITIES (BY SIMILARITY), TREMBL:Q7VCN2 (55% identity). InterPro (IPR002296): N6 adenine-specific DNA methyltransferase,N12 class. InterPro (IPR003356): N-6 DNA methylase. InterPro (IPR003665): Type I restriction-modification system M subunit. Pfam (PF02384): N-6 DNA Methylase. Pfam (PF02506): Type I restriction modification system, M protein; High confidence in function and specificity.
  
  
 0.464
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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