STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vsrPutative hypothetical very short patch repair endonuclease. Homology to vrs of E. coli of 29% (sprot|VSR_ECOLI) All proteins in this family for which functions are known are G:T mismatch endonucleases that function in a specialized mismatch repair process used usually to repair G:T mismatches in specific sections of the genome. Interpro: DNA mismatch endonuclease vsr (IPR004603) Pfam: DNA mismatch endonuclease Vsr Tigrfam: vsr: DNA mismatch endonuclease no signal peptide no TMHs; Family membership. (129 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.806
azo0355
Conserved hypothetical protein. Homology to lpg1234 of L.pneumophila of 42% (gnl|keqq|lpn:lpg1234(KEGG)). Has PF04471, Restriction endonuclease;IPR007560, Mrr_cat; Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA. No TMHs. No signal peptide.
     
 0.788
azo0358
Putative two-component sensor kinase; Region start changed from 382943 to 383189 (246 bases).
 
     0.681
azo0354
Putative methylase; Region start changed from 377491 to 377176 (315 bases); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
   
 0.572
azo0357
Hypothetical protein.
       0.572
azo0771
Probable C-5 cytosine-specific DNA methylase InterPro: C-5 cytosine-specific DNA methylase.
 
   
 0.541
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.