STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fer21Putative ferredoxin 2fe-2s protein. Homology to fer2 of C. pasteruianum of 35% (sprot|FER2_CLOPA). Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. no signal peptide no TMHs; Family membership. (106 aa)    
Predicted Functional Partners:
hoxF
Probable hydrogen dehydrogenase, alpha subunit. Homology to hoxF of A. eutrophus of 41% (sprot|HOXF_ALCEU). SUBUNITS ALPHA AND GAMMA OF HOXS CONSTITUTE AN NADH-OXIDOREDUCTASE. InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit (IPR001949); Respiratory-chain NADH dehydrogenase 24 Kd subunit (IPR002023) Pfam: Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit no signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.938
fdh1B
Probable formate dehydrogenase (NADP+), beta subunit Homology to fdh1B of M. extorpuens of 55% (trembl|Q8KTI8) Pfam: Respiratory-chain NADH dehydrogenase 24 kD subunit; Respiratory-chain NADH dehydrogenase 51 kD subunit. no signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.934
nuoE
NADH-ubiquinone oxidoreductase 24 kDa subunit mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3). TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. COMPONENT OF THE FLAVOPROTEIN-SULFUR (FP) FRAGMENT OF THE ENZYME. InterPro: Respiratory-chain NADH dehydrogenase 24 Kd subunit L12: ribosomal protein L7/L12; High confidence in function and specificity.
 
 
 0.859
azo0362
Conserved hypothetical protein. Homology to rsc0328 of R. solanacearum of 59% (trembl|Q8Y2K7). Pfam: Prolyl oligopeptidas family no signal peptide no TMHs.
 
     0.839
nasA
Probable Nitrate reductase. Homology to nasA of K. oxytoca of 41% (sprot|NASA_KLEOX). Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants fungi and bacteria. InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain no signal peptide no TMH Helixturnhelix motif; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 0.835
fdhA1
Probable formate dehydrogenase (NADP+), alpha subunit. Homology to fdh1A of M. extorquens of 60% (trembl|Q8KTI7). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655); Respiratory-chain NADH dehydrogenase 75 kD subunit (IPR000283); Ferredoxin (IPR001041); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Pfam: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-2S binding doami; Molybdopterin oxidase; Molybdopterin dinucloetide binding no signal peptide no TMHs; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase [...]
  
 0.835
fdhA2
Probable formate dehydrogenase alpha subunit. Homology to fdha of W. succinogenes of 44% (pir|S18213) The formate dehydrogenase catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655) Pfam: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain singal peptide no TMHs; High confidence in function and specificity.
  
 0.835
azo0364
Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal p [...]
       0.725
azo0361
Conserved hypothetical glutathione S-transferase protein. Homology to cv3306 of C. violaceum of 50% (trembl|Q7NSW3). Conjugation of reduced glutathione to a variety of targets. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain. no signal peptide. no TMHs; Conserved hypothetical protein.
       0.701
nuoM
Putative NADH-ubiquinone oxidoreductase, chain M; NADH-quinone oxidoreductase chain M (EC 1.6.99.5) (NADH dehydrogenase I chain M) (NDH-1 chain M). NDH-1 shuttles electrons from NADH via FMN and iron- sulfur (Fe-S) centers to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred four hydrogen ions are translocated across the cytoplasmic membrane) and thus conserves the redox energy in a proton gradient. InterPro: NADH-Ubiquino [...]
  
  
 0.678
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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