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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
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csdBCysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. (610 aa)    
Predicted Functional Partners:
iscU
NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.988
nifU
Probable nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 0.981
nifQ
Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership.
  
 0.975
mmpI
Probable immunodominant 35 kDa protein. Homology to mmpI of Mycobacterium avium of 69% (gi|2498566|sp|Q48899|MMP1_MYCAV(SwissProt (ExPASy)). No domains predicted. No signal peptide. No TMHs.,; High confidence in function and specificity.
 
  
  0.956
selD
Probable selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.884
trxB2
Thioredoxin-disulfide reductase(EC 1.8.1.9). Homology to trxB of E. coli of 71% (sprot|TRXB_ECOLI). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; High confidence in function and specificity.
 
 
  0.879
nifS
Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
    
0.846
iscS1
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
    
0.846
iscS2
Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership.
    
0.846
azo0365
Conserved Hypothetical protein, Q82Y48,Rhodanese type protein. Has SMART SM00450 Rhodanese Homology Domain(RHOD)starting at position 47-153aa;Rhodanese, a sulfurtransferase involved in cyanide detoxification (see IPR001307) shares evolutionary relationship with a large family of proteins. No Signal peptide or TMH reported Present; Family membership.
 
  
 0.824
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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