STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
csdBCysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. (610 aa)    
Predicted Functional Partners:
iscU
NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.988
nifU
Probable nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 0.986
nifQ
Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership.
  
 0.976
mmpI
Probable immunodominant 35 kDa protein. Homology to mmpI of Mycobacterium avium of 69% (gi|2498566|sp|Q48899|MMP1_MYCAV(SwissProt (ExPASy)). No domains predicted. No signal peptide. No TMHs.,; High confidence in function and specificity.
 
  
 0.955
selD
Probable selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.912
trxB2
Thioredoxin-disulfide reductase(EC 1.8.1.9). Homology to trxB of E. coli of 71% (sprot|TRXB_ECOLI). Catalyse the reaction: thioredoxin + nadp(+) = thioredoxin disulfide + nadph Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; High confidence in function and specificity.
 
 
 0.911
azo0742
Conserved hypothetical protein. Homology to rs04427 of R. solanacearum of 55% (trembl|Q8Y267). Pfam: Endonuclease/Exonuclease/phosphatase family (PF03372). Interpro: Endonuclease/Exonuclease/phosphatase family (IPR005135). no signal peptide. no TMHs.
    
   0.850
azo1419
Conserved hypothetical protein. Homology to Rsc1208 of R. solanacearum of 45% (trembl|Q8Y036). InterPro: AP endonucleases family 1 (IPR000097) tigrfam: xth: exodeoxyribonuclease III (xth) All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family 1 no signal peptide no TMHs.
    
   0.850
azo1782
Conserved hypothetical protein. Homology to mlr2853 of M. loti of 31% (trembl|Q98HI7). Tigrfam: xth: exodeoxyribonuclease III (xth). All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family I. no signal peptide. no TMHs.
    
   0.850
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.722
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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