STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0372Conserved hypothetical protein; Entry name SWISSPROT:YHBT_ECOLI Prim. accession # P45474 InterPro IPR003033; SCP2. Pfam PF02036; SCP2; 1. Prediction: Non-secretory protein Signal peptide probability: 0.001 Number of predicted TMHs: 0 Identities = 46/107 (42%). (172 aa)    
Predicted Functional Partners:
azo0373
Conserved hypothetical peptidase. Homology to Rsp0969 of R. solanacearum of 51% (trembl|Q8XR90). Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership.
 
  
 0.987
azo0374
Conserved hypothetical peptidase. Homology to cv4084 of C. violaceum of 64% (trembl|Q7NQQ39. Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership.
 
  
 0.961
azo3775
Hypothetical protein; Collagenase and related proteases. Homology to ne1979 of N. europaea of 63% (trembl|Q82TC1). InterPro: Peptidase family U32 (IPR001539). Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership; ORF9.
 
  
 0.560
azo3087
Conserved hypothetical protein. Homology to CV2710 of C.violaceum of 41% (trembl:Q7NUI8). Pfam: Hemerythrin HHE cation binding domain Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor MP2_NERDI binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two at [...]
 
     0.502
nosL
Putative NosL protein. Homology to nosL of S. meliloti of 38% (trembl|O07331). NosL is one of the accessory proteins of the nos (nitrous oxide reductase) gene cluster. NosL is a monomeric protein of 18,540 MW that specifically and stoichiometrically binds Cu(I). The copper ion in NosL is ligated by a Cys residue, and one Met and one His are thought to serve as the other ligands. It is possible that NosL is a copper chaperone involved in metallocenter assembly. probable signal peptide no TMHs; Family membership.
  
    0.494
nosRa
Transcriptional activator for nitrous-oxide reductase, N-terminal domain; Regulatory protein nosR. Transcriptional activation of the nitrous-oxide reductase gene nosZ. Similar to SWISSPROT: sprot|NOSR_PSEST (37% Pseudomonas stutzeri (Pseudomonas perfectomarina), regulatory protein NosR). TMHMM reporting 5 transmembrane helices. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
 
    0.479
azo1251
Conserved hypothetical peptidase. Homology to cv0266 of C. violaceum of 58% (cvi:CV0266). InterPro: Peptidase family U32 Pfam: Peptidase family U32 no signal peptide no TMHs; Family membership.
 
  
 0.475
azo3085
Conserved hypothetical membrane protein. Homology to CV2709 of Chromobacterium violaceum of 40% (trembl|Q7NUI9). Has PF04550;Phage holin family 2:Holins are a diverse family of proteins that cause bacterial membrane lysis during late-protein synthesis. It is thought that the temporal precision of holin-mediated lysis may occur through the buildup of a holin oligomer which causes the lysis. IPR007633;Phage_holin_2. TMHMM2 reporting 12 TMH's Present. no signal peptide; Conserved hypothetical protein.
 
     0.472
nosD
Copper-binding periplasmic protein precursor. INVOLVED IN COPPER PROCESSING AND TRANSPORT; IN THE ASSEMBLY OF THE COPPER CHROMOPHORES OF NITROUS OXIDE REDUCTASE.Part of the ABC transporter complex nosDFY involved in copper import. Similar to the putative periplasmic-binding protein nosD precursor from: P.fluorescens (36%)TREMBL:Q9F0W3 InterPro:IPR006633; CASH. IPR007742; NosD.IPR006626; PbH1. Pfam:PF05048; NosD; 1. Signal peptide: present; High confidence in function and specificity.
 
    0.465
nnrS
NnrS is a putative heme-Cu protein and a member of the short-chain dehydrogenase family, probably involved in the nitric oxide metabolism. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase. 40% NnrS. TMhelix:10 Pfam:PF05940; NnrS; 1; Function unclear.
 
     0.455
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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