STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phbC1Probable poly-beta-hydroxybutyrate synthase; Function:-Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name TREMBL:Q8KXD5 Prim. accession # Q8KXD5 Identities = 354/607 (58%) InterPro IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Number of predicted TMHs: 0; High confidence in function and specificity. (609 aa)    
Predicted Functional Partners:
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
     
 0.901
phaC
Probable polyhydroxyalkanoate synthase; Entry name :- TREMBL:Q9ZB54 Prim. accession # Q9ZB54 Identities = 290/560 (51%) InterPro:- IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam:- PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Prediction: Signal peptide Signal peptide probability: 0.999 Number of predicted TMHs: 0; Family membership.
  
  
 
0.899
phbC2
Probable poly-beta-hydroxybutyrate synthase; FUNCTION: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name :-PHBC_AZOCA Primary accession number:- O66392 Identity:-41% InterPro :-IPR000073; A/b_hydrolase. Pfam:- PF07167; PhaC_N; 1. Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership.
  
  
 
0.899
phbB1
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (60% identity); TREMBL:Q8XYX3 (59% identity). Pfam (PF00106): Short chain dehydrogenase; High confidence in function and specificity.
  
  
 0.845
pta
Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein.
 
 0.840
phbB2
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,SWISSPROT:P14697 (62% identity); TREMBL:Q8XYX3 (62% identiy). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase. SignalP reporting signal peptide; High confidence in function and specificity.
  
  
 0.831
phbF
Conserved hypothetical protein; phbF protein, 57% identity to TrEMBL;Q7NYA7. Has 2 copies of PF05233, PHB accumulation regulatory domain;IPR007897, PHB_accumulat: The proteins this domain is found in are typically involved in regulating polymer accumulation in bacteria, particularly poly-beta-hydroxybutyrate (PHB); High confidence in function and specificity.
 
   
 0.726
azo0390
Conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices; Specificity unclear.
       0.678
azo1513
Probable hydrolase; TREMBL:Q8XZ32: 54% identity, 66% similarity Probable Hypothetical protein Rv2715/MT2788/Mb2734. InterPro:IPR000073; A/b_hydrolase. IPR003089; AB_hydrolase. IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 InterPro: Alpha/beta hydrolase fold Mtu_fam_11: Mycobacterium tuberculosis pa; Family membership.
  
   
 0.592
azo0388
Conserved hypothetical protein. Homology to ebA3626 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA3626(KEGG)). InterPro: Protein of unknown function DUF132 InterPro:IPR002850; DUF132. IPR002716; PIN. IPR006596; PINc. Pfam:PF01850; PIN; SMART:SM00670; PINc; TIGRFAMs:TIGR00305; DUF132 TIGR00305: conserved hypothetical protein T. Non-secretory protein with very low signalpeptide probability (0.003) (Signal P predicted). Absence of transmembrane helices.
       0.578
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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