Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0390Conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices; Specificity unclear. (342 aa)    
Predicted Functional Partners:
phbC1
Probable poly-beta-hydroxybutyrate synthase; Function:-Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation. Entry name TREMBL:Q8KXD5 Prim. accession # Q8KXD5 Identities = 354/607 (58%) InterPro IPR000073; A/b_hydrolase. IPR010941; PhaC_N. Pfam PF00561; Abhydrolase_1; 1. PF07167; PhaC_N; 1. Number of predicted TMHs: 0; High confidence in function and specificity.
       0.670
azo0391
Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership.
 
     0.629
azo3948
Putative DNA-directed polymerase III; Excinuclease cho (EC 3.1.25.-) (Endonuclease cho) (UvrC homolog protein). Incises the DNA at the 3 side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5 site of a lesion. When a lesion remains because uvrC is not able to induce the 3 incision cho incises the DNA. Then uvrC makes the 5 incision. The combined action of cho and uvrC broadens the substrate range of nucleotide excision repair (By similarity); Specificity unclear.
    
 0.628
azo1211
Conserved hypothetical protein. Homology bll7767 of B. japonicum of 30% (trembl|Q89CN0) Pfam: WD domain, G-beta repeat no signal peptide no TMHs.
    
  0.602
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
     
 0.601
FtsJ
Ribosomal RNA large subunit methyltransferase j; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
     
  0.589
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
     
  0.589
azo0388
Conserved hypothetical protein. Homology to ebA3626 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA3626(KEGG)). InterPro: Protein of unknown function DUF132 InterPro:IPR002850; DUF132. IPR002716; PIN. IPR006596; PINc. Pfam:PF01850; PIN; SMART:SM00670; PINc; TIGRFAMs:TIGR00305; DUF132 TIGR00305: conserved hypothetical protein T. Non-secretory protein with very low signalpeptide probability (0.003) (Signal P predicted). Absence of transmembrane helices.
 
     0.559
azo0709
Putative exoribonuclease II (EC: 3.1.13.1), RNase R.
     
  0.557
vacB
Exoribonuclease II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
     
  0.557
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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