| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0390 | azo0391 | azo0390 | azo0391 | Conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices; Specificity unclear. | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | 0.629 |
| azo0390 | azo0392 | azo0390 | azo0392 | Conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices; Specificity unclear. | Conserved hypothetical protein; Similar to TREMBL:Q8YBL0 (47% identity); TREMBL:Q987R7 (50% identity); TREMBL:Q7WA35 (55% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; Function unclear. | 0.438 |
| azo0391 | azo0390 | azo0391 | azo0390 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | Conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices; Specificity unclear. | 0.629 |
| azo0391 | azo0392 | azo0391 | azo0392 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | Conserved hypothetical protein; Similar to TREMBL:Q8YBL0 (47% identity); TREMBL:Q987R7 (50% identity); TREMBL:Q7WA35 (55% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; Function unclear. | 0.587 |
| azo0391 | azo1490 | azo0391 | azo1490 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | 0.646 |
| azo0391 | azo1817 | azo0391 | azo1817 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...] | 0.641 |
| azo0391 | dnaN | azo0391 | azo0002 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...] | 0.664 |
| azo0391 | dnaX | azo0391 | azo0957 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | DNA polymerase III subunit Tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.758 |
| azo0391 | gltB | azo0391 | azo3642 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.856 |
| azo0391 | holA | azo0391 | azo3217 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; High confidence in function and specificity. | 0.664 |
| azo0391 | holB | azo0391 | azo1596 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | 0.625 |
| azo0391 | mvaB | azo0391 | azo3065 | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | Hydroxymethylglutaryl-CoA lyase, MvaB. It catalyses the conversion of (S)-3-hydroxy-3-methylglutaryl-CoA to acetyl-CoA and acetoacetate during the final step of ketogenesis and leucine catabolism. Similar to trembl|Q8QGJ4 (60%) and to pir|H83394 (56%). InterPro (PF00682): HMG-CoA Lyase-like family; High confidence in function and specificity. | 0.579 |
| azo0392 | azo0390 | azo0392 | azo0390 | Conserved hypothetical protein; Similar to TREMBL:Q8YBL0 (47% identity); TREMBL:Q987R7 (50% identity); TREMBL:Q7WA35 (55% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; Function unclear. | Conserved hypothetical protein. TREMBL:Q8Y2Q4-47% identity, 61% similarity. Pfam: Lactamase_B,aminotransferase III, AP2 domain. TMHMM predicted transmembrane helices; Specificity unclear. | 0.438 |
| azo0392 | azo0391 | azo0392 | azo0391 | Conserved hypothetical protein; Similar to TREMBL:Q8YBL0 (47% identity); TREMBL:Q987R7 (50% identity); TREMBL:Q7WA35 (55% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; Function unclear. | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | 0.587 |
| azo1490 | azo0391 | azo1490 | azo0391 | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | 0.646 |
| azo1490 | azo1817 | azo1490 | azo1817 | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...] | 0.996 |
| azo1817 | azo0391 | azo1817 | azo0391 | Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...] | Putative MerR-family transcriptional regulator,copper efflux regulator / copper export regulator) InterPro: IPR000551 HTH_MerR. HTH reporting nucleic acid binding motif; Family membership. | 0.641 |
| azo1817 | azo1490 | azo1817 | azo1490 | Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...] | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | 0.996 |
| azo1817 | dnaN | azo1817 | azo0002 | Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...] | DNA-directed DNA polymerase; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of repl [...] | 0.462 |
| azo1817 | gltB | azo1817 | azo3642 | Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...] | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.588 |