STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0398Putative beta lactamase; Probable Hypothetical protein ycbL. TREMBL:Q8Y2S7-43% identity,57% similarity. TIGRFAM:2A0115-Benzoate transport proteins belong to this group. Benzyl alcohol,benzaldehyde, benzoate, and anthranilate are metabolized via catechol, cis,cis-muconate, and the beta-ketoadipate pathway in some bacteria InterPro: Metallo-beta-lactamase superfamily Pfam:Metallo Beta lactamase superfamily, Phage lysozyme TMHMM predicted transmembrane heleces ftsZ: cell division protein FtsZ; Function unclear. (305 aa)    
Predicted Functional Partners:
azo0396
Conserved hypothetical protein. Homology to cc1308 of C. crescentus of 35% (trembl|Q9A8P5). Pfam:DUF1289 This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. no signal peptide no TMHs.
 
     0.829
azo0397
Hypothetical protein, 54% identity to TrEMBl;Q8YGQ7. Has PF06945, Protein of unknown function (DUF1289);IPR010710;This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown.
       0.783
azo3727
Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present; Conserved hypothetical protein.
  
     0.677
azo3728
Probable lipoprotein, 58% similarity to TrEMBL:Q8XWT8 PROBABLE LIPOPROTEIN [RS01163] [Ralstonia solanacearum (Pseudomonas solanacearum)]. Has PF04355:IPR007450:SmpA / OmlA family;Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope [1]. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (OmpA). Signal peptide present. NO TMH reported present; Family membership.
  
     0.671
azo0395
2-hydroxychromene-2-carboxylate isomerase family protein; Similar to TREMBL:Q8Y2R2 (42% identity); TREMBL:Q7WEK4 (30% identity); TREMBL:Q88IW7 (27% identity). Pfam (HCCA_isomerase): 2-hydroxychromene-2-carboxylate isomerase; Family membership.
  
    0.639
azo2279
Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [...]
   
 0.608
azo0364
Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal p [...]
  
     0.593
gloA1
Glyoxalase I (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway in the following reaction: glutathione + methylglyoxal = (R)-S-lactoylglutathione,; Function unclear.
  
  
  0.577
azo0152
Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein.
  
     0.568
azo0399
Conserved hypothetical protein; Displays ATPase and GTPase activities.
       0.567
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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