STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cheDConserved hypothetical chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (196 aa)    
Predicted Functional Partners:
azo2479
Conserved hypothetical membrane protein. Homology to VV12384 of Vibrio vulnificus of 60% (trembl|Q8DA26). No domains predicted. TMHMM2 reporting 1 TMH present. No signal peptide present; Conserved hypothetical protein.
 
 0.993
cheB1
Probable protein glutamate-methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.992
cheR1
Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
  
 0.976
cheB2
Protein glutamate-methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.976
azo2270
Methyl-accepting chemotaxis transducer,; Specificity unclear.
 
  0.969
cheA1
Putative chemotaxis histidine kinase protein,ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. Chemotaxis protein cheA (EC 2.7.3.-). INVOLVED IN THE TRANSMISSION OF SENSORY SIGNALS FROM THE CHEMORECEPTORS TO THE FLAGELLAR MOTORS. CHEA IS AUTOPHOSPHORYLATED; IT CAN TRANSFER ITS PHOSPHATE GROUP TO EITHER CHEB OR CHEY; High confidence in function and specificity.
 
 
 0.966
azo0091
Methyl-accepting chemotaxis protein,; Specificity unclear.
 
  0.961
azo0406
Methyl-accepting chemotaxis protein, only very low similarity to SWISSPROT: sprot|Y4FA_RHISN (14% Rhizobium sp. (strain NGR234). InterPro: IPR004090; Me_chemotaxis. IPR004089; Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices; Family membership.
 
  0.959
azo0407
Methyl-accepting chemotaxis protein, only very low similarity to SWISSPROT: sprot|Y4FA_RHISN (14% Rhizobium sp. (strain NGR234). InterPro: IPR004090; Me_chemotaxis. IPR004089; Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices; Family membership.
 
  0.955
cheW1
Probable positive regulator of CheA protein activity, CheW. Pfam: PF01584; CheW. SMART: SM00260; CheW. Chemotaxis protein cheW.Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges chea to the mcps (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to cheY and cheB; High confidence in function and specificity.
 
 
 0.944
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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