Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cpoBConserved hypothetical secreted protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (239 aa)    
Predicted Functional Partners:
tolB
Putative translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.989
pal
Putative peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.931
queE
Conserved hypothetical radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.823
tolQ
Translocation protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.820
tolR
Putative translocation protein TolR. Holomology to tolR of P. aeruginosa of 30% (sprot|TOLR_PSEAE) Involved in eth TonB-independent uptake of proteins. no signal peptide probable 1 TMH; Family membership.
 
  
 0.754
surA
Putative peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
  
   0.720
exsB
Conserved hypothetical ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
       0.718
ppiD
Putative peptidyl-prolyl cis-trans isomerase. Homology to ppiD of E. coli of 23% (sprot|PPID_ECOLI). PPIASES ACCELERATE THE FOLDING OF PROTEINS. SEEMS TO BE INVOLVED IN THE FOLDING OF OUTER MEMBRANE PROTEINS. InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain probable 1 TMH no signal peptide; Family membership.
 
   0.705
azo0412
Conserved hypothetical membrane protein. Homology to rsc0739 of R. solanacearum of 52% (trembl|Q8Y1F1). Pfam: DUF395 This family includes YeeE and YedE from E. coli. These proteins are integral membrane proteins of unknown function. Many of these proteins contain two homologous regions that are represented by this family. This region contains several conserved glycines and an invariant cysteine that is probably an important functional residue. signal peptide 8 TMHs; Conserved hypothetical protein.
       0.697
azo0421
Conserved hypothetical thioesterase. Homology to bb4233 of B. bronchiseptica of 41% (trembl|Q7WFN8). Tigrfam: TIGR00051: conserved hypothetical protein .Pfam: 4-hydroxybenzol-CoA thioesterase (PF0361). Interpro: 4-hydroxybenzol-CoA thioesterase (IPR006684); thioesterase superfamily (IPR006683) This family contains a wide variety of enzymes, principally thioesterases. This family includes 4HBT which catalyses the final step in the biosynthesis of 4-hydroxybenzoate from 4-chlorobenzoate in the soil dwelling microbe Pseudomonas CBS-3. This family includes various cytosolic long-chain acyl [...]
 
   
 0.666
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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