Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0433Conserved hypothetical membrane protein. Homology to bll1489 of B. japonicum of 58% (trembl|Q89UC8(SRS)) InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81 Presence of 8 transmembrane helices (TMHMM predicted) probable transmembrane protein of unknown function) no signal peptide; Conserved hypothetical protein. (259 aa)    
Predicted Functional Partners:
cysI
Putative sulfite reductase; 49% Fd-NiR.IPR011255; NiR_SiRalpha_1/3.IPR006067; Nir_Sir_4Fe4S.IPR005117; NiR_SiR_beta_fer. Pfam:PF01077; NIR_SIR; 2.PF03460; NIR_SIR_ferr; 2; High confidence in function and specificity.
 
   
 0.737
azo0431
Conserved hypothetical protein. Homology to PA1837 of P.aeruginosa of 50% (tremble:Q9I2Q8). Has PF06073,Bacterial protein of unknown function (DUF934);IPR008318 UCP030820: This family consists of several bacterial proteins of unknown function. One of the members of this family Q8YEW3 is thought to be an oxidoreductase. No signal peptide. No TMHs.
 
     0.736
cysH
Probable phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.716
cysB
HTH-type transcriptional regulator cysB (Cys regulon transcriptional activator). this protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of l-cysteine from inorganic sulfate. the inducer for cysb is n-acetylserine. cysb inhibits its own transcription; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
 
     0.628
cysD
Putative sulfate adenylyltransferase subunit 2; 84% PAPS_reduct. Pfam:PF01507; PAPS_reduct; 1; High confidence in function and specificity.
  
  
 0.483
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
    
 0.457
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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