STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysBHTH-type transcriptional regulator cysB (Cys regulon transcriptional activator). this protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of l-cysteine from inorganic sulfate. the inducer for cysb is n-acetylserine. cysb inhibits its own transcription; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. (313 aa)    
Predicted Functional Partners:
azo0433
Conserved hypothetical membrane protein. Homology to bll1489 of B. japonicum of 58% (trembl|Q89UC8(SRS)) InterPro:IPR002781; DUF81. Pfam:PF01925; DUF81 Presence of 8 transmembrane helices (TMHMM predicted) probable transmembrane protein of unknown function) no signal peptide; Conserved hypothetical protein.
 
     0.634
gltR
Probable transcriptional regulator, LysR family; HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.585
cysI
Putative sulfite reductase; 49% Fd-NiR.IPR011255; NiR_SiRalpha_1/3.IPR006067; Nir_Sir_4Fe4S.IPR005117; NiR_SiR_beta_fer. Pfam:PF01077; NIR_SIR; 2.PF03460; NIR_SIR_ferr; 2; High confidence in function and specificity.
     
 0.535
cysH
Probable phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite.
     
 0.533
azo0431
Conserved hypothetical protein. Homology to PA1837 of P.aeruginosa of 50% (tremble:Q9I2Q8). Has PF06073,Bacterial protein of unknown function (DUF934);IPR008318 UCP030820: This family consists of several bacterial proteins of unknown function. One of the members of this family Q8YEW3 is thought to be an oxidoreductase. No signal peptide. No TMHs.
       0.532
ampR
Probable transcriptional regulator, LysR family; Probable HTH-type transcriptional activator ampR. Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (ampC) in the presence of beta-lactams and induces it in the absence of them. Similar to SWISSPROT: sprot|AMPR_PSEAE (34% Pseudomonas aeruginosa,HTH-type transcriptional activator AmpR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.492
azo1636
HTH-type transcriptional regulator,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.490
azo0435
Hypothetical secreted protein. No homology to the data bank. No domains predicted. Signal peptide present. No TMHs.
       0.480
ptxR
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.478
hupR
Transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.471
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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