STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kefBGlutathione-regulated potassium-efflux system protein kefB,(K+/H+ antiporter).Transport system that facilitates potassium-efflux possibly by potassium-proton antiport. 32% K_eff.IPR006153; Na_H_porter.IPR006036;TrkA_Kuptake. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA-N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMHelix:12. Belongs to the monovalent cation:proton antiporter 2 (cpa2) transporter (TC 2.A.37) family. KefB subfamily; High confidence in function and specificity. (588 aa)    
Predicted Functional Partners:
drgA
Putative NAD(P)H oxidoreductase HI1544 (EC 1.6.5.2). trembl:Q88J60: 64% identity; 80% similarity This family consists of bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC: 1.6.5.2 that catalyses the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species [1]. This enzyme uses a FAD co-factor InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavodoxin_2 SignalP predicted signal peptide present No transmembrane helices (TMHMM predicted); High confidence in function and specificity.
   
 
 0.912
nqo1
NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (QR1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase). The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis (By similarity). trembl:Q9I4B4:72%identity; 81% similarity InterPro: NAD(P)H dehydrogenase (quinone) InterPro:IPR003680; NADHdh_2. Pfam:PF02525; Flavo [...]
   
 
 0.912
flgG
Flagellar basal-body rod protein flgG (Distal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
    
   0.858
dctD1
C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity.
       0.773
dctB1
Sensor histidine kinase; C4-dicarboxylate transport sensor protein,; High confidence in function and specificity.
       0.773
rosB
Putative Potassium/proton antiporter; Probable potassium antiporter, rosB. 38% HPr_SerP_S.IPR004771; K_eff.IPR006153; Na_H_porter. IPR003148; TrkA_N. Pfam:PF00999; Na_H_Exchanger; 1.PF02254; TrkA_N; 1. TIGRFAMs:TIGR00932; 2a37; 1. TMhelix: 12; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.669
azo0450
PAS/PAC/GGDEF-domain containing protein,implicating involvement into signalling processes. Similarity to TREMBL: trembl|Q98JA6 (30% Rhizobium loti,hypothetical protein mlr2027) InterPro: IPR000160 GGDEF. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. Pfam: PF00990 GGDEF. SMART: SM00086 PAC. SM00091 PAS. TIGRFAM: TIGR00254 GGDEF. TIGR00229 sensory_box.
       0.526
azo0346
Putative Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
   
 
 0.492
etf1
Probable electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
  
  
 0.483
etf2
Probable electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
  
  
 0.483
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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