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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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[Homology]
Score
fadEProbable acyl-CoA dehydrogenase. Homology to fadE of E. coli of 55% (trembl|Q8KTJ8(SRS)) Catalyzes the dehydrogenation of acyl-CoA (By similarity). Reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. InterPro: Acyl-CoA dehydrogenase (IPR006089) Pfam: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain signal peptide 2 TMHs; High confidence in function and specificity. (823 aa)    
Predicted Functional Partners:
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
 
 0.998
fadA1
Probable 3-ketoacyl-CoA thiolase; Subunit of fatty acid oxidation complex, 3-keto-acyl-coa-thiolase. Activity:-acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name TREMBL:Q8G967 Prim. accession # Q8G967 Identities = 284/425 (66%) InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.987
fadB2
Short-chain enoyl-CoA hydratase activity. Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership.
 
 0.975
paaF1
Probable enoyl-CoA hydratase; COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). CATALYTIC ACTIVITY: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Entry name :- SWISSPROT:PAAF_ECOLI Prim. accession # P76082 InterPro :- IPR001753; EnCoA_hydrtse. Pfam :- PF00378; ECH; 1. Identities = 109/250 (43%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.956
fadA2
Probable 3-ketoacyl-CoA thiolase; Activity:- acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name:- SWISSPROT:THIK_ECOLI Prim. accession # P21151 InterPro:- IPR002155; Thiolase. Pfam:-PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 177/400 (44%) Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.929
thlA
Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase):- catalytic activity:-2 acetyl-coa = coa + acetoacetyl-coa. Entry name SWISSPROT:THLA_CLOAB Prim. accession # P45359 Identities = 205/392 (52%) InterPro IPR002155; Thiolase. Pfam PF00108; thiolase; 1. Prediction: Non-secretory protein Signal peptide probability: 0.022 Number of predicted TMHs: 0; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.922
fadAx
Probable acyl-CoA thiolase. Homology to fadAx of P. putida of 67% (gnl|keqq|ppu:PP2215(KEGG)). IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC:2.3.1.9) and 3-ketoacyl-CoA thiolase (EC:2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid -oxidation. Acetoacetyl-CoA thiolase (also called thiolase II) is specific for the thiolysis of a [...]
   
 0.905
fadfX
Probable acyl-CoA dehydrogenase; Activity:- Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q9AHX9 Prim. accession # Q9AHX9 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Identities = 244/375 (65%) Number of predicted TMHs: 0; Family membership.
     
  0.855
azo0466
Conserved hypothetical acyl-CoA thioesterase. Homology to an orf of Azoarcus sp. EbN1 (trembl|Q8G9D6). Pfam: cytosolic long-chain acyl-CoA thioesterase Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. Interpro: Thioesterase superfamily (IPR006683) no signal peptide no. TMHs; Family membership.
    
 0.827
paaG1
Probable enoyl-CoA hydratase. Homology to paaG of E. coli of 60% (sprot|PAAG_ECOLI(SRS) COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Interpro: Enoyl-CoA hydratase/isomerase (IPR001753) Pfam: Enoyl-CoA hydratase/isomerase no signal peptide no TMHs; High confidence in function and specificity.
   
 0.764
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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