STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo0466Conserved hypothetical acyl-CoA thioesterase. Homology to an orf of Azoarcus sp. EbN1 (trembl|Q8G9D6). Pfam: cytosolic long-chain acyl-CoA thioesterase Long-chain acyl-CoA hydrolases hydrolyse palmitoyl-CoA to CoA and palmitate, they also catalyse the hydrolysis of other long chain fatty acyl-CoA thioesters. Interpro: Thioesterase superfamily (IPR006683) no signal peptide no. TMHs; Family membership. (134 aa)    
Predicted Functional Partners:
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
   
 0.917
fadA1
Probable 3-ketoacyl-CoA thiolase; Subunit of fatty acid oxidation complex, 3-keto-acyl-coa-thiolase. Activity:-acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name TREMBL:Q8G967 Prim. accession # Q8G967 Identities = 284/425 (66%) InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.834
fadE
Probable acyl-CoA dehydrogenase. Homology to fadE of E. coli of 55% (trembl|Q8KTJ8(SRS)) Catalyzes the dehydrogenation of acyl-CoA (By similarity). Reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. InterPro: Acyl-CoA dehydrogenase (IPR006089) Pfam: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain signal peptide 2 TMHs; High confidence in function and specificity.
    
 0.828
fadB2
Short-chain enoyl-CoA hydratase activity. Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership.
   
 0.791
fadL
Long-chain fatty acid transport protein precursor (Outer membrane fadL protein) (Outer membrane flp protein). Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel (By similarity). Entry name:- Q8G9D7 Primary accession number:-Q8G9D7 InterPro:- IPR005017; Toluene_X. Pfam:- PF03349; Toluene_X; 1. identity:- 66% Prediction: Signal peptide Signal peptide probability: 1.0 Number of predicted TMHs: 0; High confidence in function and specificity.
       0.601
azo1267
Probable acyl-CoA thioester hydrolase; Entry name TREMBL:Q7W380 Prim. accession # Q7W380 Identities = 111/150 (74%) InterPro IPR006683; Thioestr_supf. Pfam PF03061; 4HBT; 1. Prediction: Non-secretory protein Signal peptide probability: 0.179 Number of predicted TMHs: 0; Family membership.
 
  
 
0.492
azo0462
Conserved hypothetical secreted protein. Homology to an orf of Trichodesmium erythraeum of 45% (gi|48892210|ref|ZP_00325608.1|(NBCI ENTREZ)). No domains predicted. Signal peptide present. No TMH present; Conserved hypothetical protein.
       0.446
sucC
Probable succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.434
fabI1
Probable enoyl-acyl carrier protein reductase; CATALYTIC ACTIVITY: Acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH Entry name:- SWISSPROT:FABI_PSEAE Prim. accession # Q9ZFE4 Identities = 173/260 (66%) InterPro :- IPR002198; ADH_short. Pfam:- PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.044 Number of predicted TMHs: 0; High confidence in function and specificity.
  
    0.433
fabI2
Probable enoyl-[acyl-carrier-protein] reductase; Catalytic activity :-acyl-[acyl-carrier protein] + nad(+) = trans- 2,3-dehydroacyl-[acyl-carrier protein] + nadh. pathway:- fatty acid biosynthesis pathway; second reduction step. Entry name SWISSPROT:FABI_ECOLI InterPro IPR002198; ADH_short. Identities = 108/252 (42%) Pfam PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0; High confidence in function and specificity.
  
    0.421
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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