STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
isoJProbable glutathione S-transferase. Homology to isoJ of Rhodococcus sp AD45 of 48% (trembl|Q9RBP3). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity. (206 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.818
azo0490
Putative acetone-cyanohydrin lyase; TREMBL:Q8F3A6: 43% identity, 60% similarity Non-heme chloroperoxidase (EC 1.11.1.10) (Chloride peroxidase) (CPO-P) (Chloroperoxidase P). CHLORINATES AND BROMINATES SUITABLE ORGANIC COMPOUNDS. INVOLVED IN THE BIOSYNTHESIS OF THE ANTIBIOTIC PYRROLNITRIN. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR003089: AB_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1; 1 TIGRFAM:dsbE: periplasmic protein thiol:disulf; Family membership.
 
     0.803
rpoC
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.742
rpoZ
DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.735
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.714
azo0361
Conserved hypothetical glutathione S-transferase protein. Homology to cv3306 of C. violaceum of 50% (trembl|Q7NSW3). Conjugation of reduced glutathione to a variety of targets. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain. no signal peptide. no TMHs; Conserved hypothetical protein.
 
  
 0.665
lysS
Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS); High confidence in function and specificity; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
  0.627
azo2485
Conserved hypothetical protein. Homology to eca2717 of E. carotovora of 35% (tremble:Q6D3M7). no domains predicted. no signal peptide. no TMHs.
   
  0.627
gor
Probable glutathione-disulfide reductase. Homology to gor of E. coli of 53% (sprot|GSHR_ECOLI). Maintain high levels of reduced glutathione in the cytosol. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); NAD binding site (IPR000205); Pyridine nuclotide-disulfide oxidoreductase dimerisation doamin (IPR004099); Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100) Pfam: Pyridine nuccleotide-dusulfphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase dimerisation domain no signal peptide no TMHs; High confidence in function and [...]
  
 
 0.614
metG
MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.600
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.