STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0492Conserved hypothetical membrane protein. Homology to BH1226 of Bacillus halodurans of 40% (pir|B83803) no domains predicted. signal peptide. 1 TMHs; Conserved hypothetical protein. (65 aa)    
Predicted Functional Partners:
ruvB
Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.749
hemX
Putative uroporphyrin-III C-methyltransferase. catalytic activity: 2 s-adenosyl-l-methionine + uroporphyrin iii = 2 s-adenosyl-l-homocysteine + sirohydrochlorin. pathway: siroheme and cobalamin biosynthesis; Specificity unclear.
  
  
 0.603
azo0490
Putative acetone-cyanohydrin lyase; TREMBL:Q8F3A6: 43% identity, 60% similarity Non-heme chloroperoxidase (EC 1.11.1.10) (Chloride peroxidase) (CPO-P) (Chloroperoxidase P). CHLORINATES AND BROMINATES SUITABLE ORGANIC COMPOUNDS. INVOLVED IN THE BIOSYNTHESIS OF THE ANTIBIOTIC PYRROLNITRIN. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR003089: AB_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1; 1 TIGRFAM:dsbE: periplasmic protein thiol:disulf; Family membership.
       0.577
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
    0.570
isoJ
Probable glutathione S-transferase. Homology to isoJ of Rhodococcus sp AD45 of 48% (trembl|Q9RBP3). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Pfam: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain no signal peptide no TMHs; High confidence in function and specificity.
       0.551
ruvA
Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
    0.410
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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