STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheCPutative cyclohexadienyl dehydratase precursor. Homology to pheC of P. aeruginosa of 36% (sprot|PHEC_PSEAE) FORMS ALTERNATIVE PATHWAY FOR PHENYLALANINE BIOSYNTHESIS. CAN CATALYZE TWO REACTIONS: PREPHENATE DEHYDRATASE AND AROGENATE DEHYDRATASE. MAY HAVE A ROLE IN CHEMOTAXIS OR TRANSPORT. InterPro: Bacterial extracellular solute-binding proteins family 3 (IPR001638), solute-binding protein/glutamate receptor (IPR001311) Pfam: Bacterial extracellular solute-binding proteins signal peptide no TMHs; Function unclear. (268 aa)    
Predicted Functional Partners:
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
 
  
 0.775
barA
Putative sensor-regulator protein,; Specificity unclear.
 
  
 0.760
azo2265
Conserved hypothetical amino acid permease. Homology to pspto5247 of P. syringae (trembl|Q87UP9). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE (BY SIMILARITY). Interpro: binding-protein-depenent transport system inner membrane component (IPR000515). Pfam: Binding-protein-dependent transport system. no signal peptide. 3 TMHs; Specificity unclear.
 
 0.759
azo0498
GGDEF/PAS/PAC-domain containing protein. Similarity to SWISSPROT: sprot|Y4LL_RHISN (13% Rhizobium sp. (strain NGR234), hypothetical 91.8 kda protein y4ll) / TREMBL: trembl|Q55955 (14% Synechocystis sp. (strain PCC 6803),sll0779) Pfam: PF00990 GGDEF domain. PF00989 PAS. PF00785 PAC. TIGRFAM: TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box. TMHMM reporting 2 transmembrane helices.
    
  0.755
azo2264
Amino acid ABC transporter, permease protein, 75% Identity to TrEMBL;Q87UQ0, 65% Identity to TrEMBL;Q8XXK9,Q6F6T8. Has PF00528; IPR000515, BPD_transp; Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown that most of these p [...]
 
 0.752
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
   
 0.733
gacS
Putative two-component hybrid sensor and regulator,; Family membership.
    
 0.725
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
   
 0.717
glnM
Putative glutamine transport permease protein. Homology to glnM of B. subtilis of 30% (TREMBL:O34671) Probably part of the binding-protein-dependent transport system of amino acids. Probably responsible for the translocation of the substrate across the membrane InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein-dependent transport systems inner membrane component no signal peptide probable 5 TMHs; Family membership.
 
 0.688
glnQ2
Probable glutamine transport ATP-binding protein. Homology with glnQ of B. stearothermophilus of 53% (sprot|GLNQ_BACST). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. InterPro: AAA ATPase superfamily (IPR003593), ABC_Transporter (IPR003439), ATP/GTP_binding site motif A (P-loop) (IPR001687) Pfam: ABC transporter no signal peptide no TMHs mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity.
 
 0.683
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.