STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recXProbable RecX-family regulatory protein; Modulates RecA activity; Belongs to the RecX family. (149 aa)    
Predicted Functional Partners:
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.985
radA
Probable DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.898
yhbG
Probable ABC transporter ATP-binding protein HI1148. ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. TREMBL:Q7NST9: 64% identity,75% similarity InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. IPR000767; Disease_resist. IPR003016; Lipoyl_BS. Pfam PF00005; ABC_tran; 1 mobB: molybdopterin-guanine dinucleoti TMH's present 0; High confidence in function and specificity.
       0.820
rpoN1
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.797
rpoX
Probable sigma 54 modulation protein,; High confidence in function and specificity.
       0.787
ruvC
Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
  
 0.676
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
  
    0.671
ygaD1
Probable CinA-related protein; Hypothetical 17.2 kDa protein 1 in recA 5region. TREMBL:Q9KUH9: 54% identity, 64% similarity CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation [1]. This is a C-terminal region of putative competence-damaged proteins from the cin operon InterPro:IPR008136; CinA_C. Pfam: PF02464; CinA cinA_cterm: competence/damage-inducible p No signal peptide. No transmembrane helices; High confidence in function and specificity.
     
 0.601
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.589
comA
Putative DNA uptake/competence protein; Competence protein comA. Essential for natural transformation. Could be a transporter involved in DNA uptake. InterPro: DNA internalization-related competence protein ComEC/Rec2 function: transporter activity TREMBL:Q82SD2: 38% identity,50% similarity. InterPro:IPR001279; Blactmase-like. IPR004477; ComEC_N-term. IPR004797; ComEC_Rec2. Pfam PF03772; Competence; 1. PF00753; Lactamase_B; 1. TIGRFAMs:TIGR00360; ComEC_N-term; 1. TIGR00361; ComEC_Rec2; ComEC_Rec2: DNA internalization-relate TMHMM predicted 8 transmembrane helices; High confidence in fu [...]
 
   
 0.587
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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