STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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azo0509Putative phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (160 aa)    
Predicted Functional Partners:
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (PGP synthase). It catalyses the conversion of CDP-diacylglycerol and glycerol-3-phosphate to CMP and 3-(3-phosphatidyl)-glycerol 1-phosphate in the commited step to the synthesis of acidic phospholipids. It is an integral membrane protein. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. Entry name :-SWISSPROT:PGSA_ECOLI Prim. accession # P06978 Identities = 50% InterPro IPR000462; CDP-OH_P_trans. I [...]
 
  
 0.934
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
  
 0.859
ygaD1
Probable CinA-related protein; Hypothetical 17.2 kDa protein 1 in recA 5region. TREMBL:Q9KUH9: 54% identity, 64% similarity CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation [1]. This is a C-terminal region of putative competence-damaged proteins from the cin operon InterPro:IPR008136; CinA_C. Pfam: PF02464; CinA cinA_cterm: competence/damage-inducible p No signal peptide. No transmembrane helices; High confidence in function and specificity.
       0.800
cls1
Putative cardiolipin synthetase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
     
 0.789
pssA
This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine. Entry name:-SWISSPROT:PSS_HELPY identity:- 34% InterPro:-IPR000462; CDP-OH_P_trans. IPR004533; PssA. Pfam:- PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.047(YES); Family membership; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.619
azo0663
Probable CDP-alcohol phosphatidyltransferase family protein; Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. Entry name Q8PQ18 Primary accession number: Q8PQ18 InterPro IPR000462; CDP-OH_P_trans. Pfam PF01066; CDP-OH_P_transf; 1. Identities = 114/203 (56%),Prediction: Signal peptide Signal peptide probability: 0.988 Number of predicted TMHs: 3; Family membership.
    
 0.575
ribD
AMP deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.571
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.561
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
       0.558
azo3139
Haloacid dehalogenase-like hydrolase family is structurally different from the alpha/beta hydrolase family (abhydrolase). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. Similar to trembl|Q82XZ3 (63%) and to pir|B83604 (47%). Pfam (PF00702): haloacid dehalogenase-like hydrolase; Family membership.
    
 0.555
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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