STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifANif-specific regulatory protein. NIFA A TRANSCRIPTIONAL ACTIVATOR IS REQUIRED FOR ACTIVATION OF MOST NIF OPERONS WHICH ARE DIRECTLY INVOLVED IN NITROGEN FIXATION. NIFA INTERACTS WITH SIGMA-54. InterPro: Sigma-54 factor interaction domain; High confidence in function and specificity. (517 aa)    
Predicted Functional Partners:
nifL
Nitrogen fixation regulatory protein (EC 2.7.3.-). Required for the inhibition of nifA activity in response to oxygen and low level of fixed nitrogen. Similar to SWISSPROT: sprot|NIFL_AZOVI (41% Azotobacter vinelandii,nitrogen fixation regulatory protein (EC 2.7.3.-), NifL) InterPro: IPR003661 His_kinA_N. The histidine kinase A (phosphoacceptor) N-terminal domain is a dimerisation and phosphoacceptor domain of histidine kinases. It has been found in bacterial sensor protein/histidine kinases. IPR000014 PAS. PAS domains are involved in many signalling proteins where they are used as a s [...]
 
 
 0.975
azo2450
Putative two-component system sensor protein,; Function unclear.
   
 0.897
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
   
 0.878
azo3381
Hypothetical signaling protein.
   
 0.873
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
   
 0.844
azo2457
Putative sensory box histidine kinase,; Function unclear.
   
 0.839
rpoN1
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.829
azo0694
Putative hybrid sensor and regulator protein,; Specificity unclear.
   
 0.825
azo2362
Putative sensor kinase/response regulator hybrid protein,; Specificity unclear.
   
 0.825
rpoN2
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.801
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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