STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nifBNitrogen fixation protein; FeMo cofactor biosynthesis protein nifB. PROBABLY INVOLVED IN THE SYNTHESIS OF THE FE-MO COFACTOR; High confidence in function and specificity. (498 aa)    
Predicted Functional Partners:
nifN
Probable nitrogenase iron-molybdenum cofactor biosynthesis protein NifN. Homology to nifN of A. vielandii of 60% (sprot|NIFN_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase probable signal peptide no TMHs; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family.
  
 0.986
nifH
Putative nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
  
 0.963
nifK
Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
  
 0.940
nifD
Nitrogenase molybdenum-iron protein alpha chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein; High confidence in function and specificity.
 
  
 0.912
nifW
Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family.
 
  
 0.909
nifQ
Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership.
 
  
 0.897
nifT
Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present; High confidence in function and specificity.
 
  
 0.893
nifE
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE. Homology to nifE of A. vielandii of 70% (sprot|NIFE_AZOVI). This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). InterPro: Oxidoreductase nitrogenase component 1 (IPR000510) Pfam: Nitrogenease component 1 type oxidoreductase no signal peptide no TMHs; High confidence in function and specificity; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.888
azo0558
Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership.
 
  
 0.869
azo0525
Conserved hypothetical protein. Homology to an orf of P. stuzeri of 49% (trembl|Q93JV4). Tigrfam: arsC: arsenate reductase. Pfam: ArsC family (PF03960) no signal peptide. no TMHs.
 
   
 0.855
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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