Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
draG1Probable ADP-ribosyl-[dinitrogen reductase] hydrolase. Homology to draG of R. rubrum of 44% (sprot|DRAG_RHORU) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase (DraT) transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: ADP-ribosylglycohydrolase no signal peptide no TMHs. (312 aa)    
Predicted Functional Partners:
nifQ
Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership.
 
     0.877
draT
Putative NAD(+)-dinitrogen-reductase ADP-D-ribosyltransferase (EC 2.4.2.37) (ADP-ribosyltransferase). Homology to draT of R. rubrum of 39% (sprot|DRAT_RHORU(SRS) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: DRAT no signal peptide no TMHs; High confidence in function and s [...]
 
   
 0.795
azo2643
Putative dual specificity protein phosphatase,; Function unclear.
      0.669
fdxD
Ferredoxin V (FdV) (Ferredoxin plant-type). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN PROBABLY PARTICIPATES IN NITROGEN FIXATION. InterPro: Ferredoxin; High confidence in function and specificity.
 
     0.637
cowN
Conserved hypothetical protein; Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
 
     0.620
fdxB
Probable ferredoxin. Homology to fdxB of R. capsulatus of 45% (sprot|FER3_RHOCA) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain no signal peptide no TMHs; Family membership.
 
     0.595
azo0525
Conserved hypothetical protein. Homology to an orf of P. stuzeri of 49% (trembl|Q93JV4). Tigrfam: arsC: arsenate reductase. Pfam: ArsC family (PF03960) no signal peptide. no TMHs.
 
     0.593
nifX
Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs; Conserved hypothetical protein.
  
   
 0.564
glnB
PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ2 (100%) and to trembl|Q8XWX5 (82%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity.
    
 
 0.547
glnY
PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ4 (100%) and to trembl|Q9RBK0 (78%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity.
    
 
 0.547
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.