STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0536Conserved hypothetical protein. Homology to an orf of Pseudomonas stutzeri of 52% (tremble:Q9EVM9). No domains predicted. No TMHs. No signal peptide. (283 aa)    
Predicted Functional Partners:
dcrH1
Putative hemerythrin-like protein; DcrH: hemerythrin protein,is a transmembrane methyl-accepting protein probably involved in bacterial chemotaxis. 36% Hemerythrin. Hemerythrin family non-heme Pfam:PF01814; Hemerythrin; 1; High confidence in function and specificity.
 
     0.943
nifT
Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present; High confidence in function and specificity.
 
    0.905
fdxC
Ferredoxin IV (FdIV) (Ferredoxin plant-type). Homology to fdxC of R. capsulatus of 62% (FER4_RHOCA). FERREDOXINS ARE IRON-SULFUR PROTEINS THAT TRANSFER ELECTRONS IN A WIDE VARIETY OF METABOLIC REACTIONS. THIS FERREDOXIN PROBABLY PARTICIPATES IN NITROGEN FIXATION. Pfam: 2Fe-2S iron-sulfur clauster binding domain no signal peptide no TMHs; High confidence in function and specificity.
  
    0.838
azo0544
ORF1; Conserved hypothetical protein. Homology to orf1 of Azoarcus sp. BH72 of 100% (gi|11493650|gb|AAG35591.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
 
     0.823
azo0558
Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership.
 
  
 0.809
nifZ
Nitrogen Fixation protein[nifZ], 51% identity (67% similarity) SwissProt;P14889,66% similarity to SwissProt;P23124. Has PF04319:NifZ domain;(IPR007415)This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal Peptide Or TMH reported Present; High confidence in function and specificity.
 
    0.807
nifY1
NifY protein. Homology to nifY of Azoarcus sp. BH72 of 99% (gi|11493644|gb|AF200742.1|AF200742(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs; Function unclear.
 
    0.801
azo1131
Conserved hypothetical protein. Homology to Daro03001685 of Dechloromonas aromatica of 46% (gi|41725028|ref|ZP_00151838.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
 
     0.798
azo0549
Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present.
 
     0.797
azo0564
Conserved hypothetical protein. Has PF05484:LRV protein FeS4 cluster(IPR008665);This Iron sulphur cluster is found at the N-terminus of some proteins containing LRV repeats. Has 6,(IPR004830) PF01816:Leucine rich repeat variant;The function of this repeat is unknown. It has an unusual structure of two helices. One is an alpha helix,the other is the much rarer 3-10 helix; Function unclear.
 
    0.795
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (26%) [HD]