| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0549 | azo0558 | azo0549 | azo0558 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | 0.782 |
| azo0549 | nifB | azo0549 | azo0523 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Nitrogen fixation protein; FeMo cofactor biosynthesis protein nifB. PROBABLY INVOLVED IN THE SYNTHESIS OF THE FE-MO COFACTOR; High confidence in function and specificity. | 0.622 |
| azo0549 | nifK | azo0549 | azo0540 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. | 0.425 |
| azo0549 | nifQ | azo0549 | azo0529 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership. | 0.767 |
| azo0549 | nifT | azo0549 | azo0541 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present; High confidence in function and specificity. | 0.767 |
| azo0549 | nifV | azo0549 | azo0551 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Homocitrate synthase is involved in the biosynthesis of the iron-molybdenum cofactor of nitrogenase and catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate into homocitrate. Similar to sprot|NIFV_AZOVI (51%) and to sprot|NIV1_ANASP (42%). Pfam (PF00682): HMG-CoA Lyase-like family InterPro (PS00815): Alpha-isopropylmalate and homocitrate synthase; High confidence in function and specificity; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.850 |
| azo0549 | nifW | azo0549 | azo0548 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family. | 0.929 |
| azo0549 | nifX | azo0549 | azo0560 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs; Conserved hypothetical protein. | 0.755 |
| azo0549 | nifZ | azo0549 | azo0547 | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | Nitrogen Fixation protein[nifZ], 51% identity (67% similarity) SwissProt;P14889,66% similarity to SwissProt;P23124. Has PF04319:NifZ domain;(IPR007415)This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal Peptide Or TMH reported Present; High confidence in function and specificity. | 0.928 |
| azo0558 | azo0549 | azo0558 | azo0549 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | 0.782 |
| azo0558 | nifB | azo0558 | azo0523 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogen fixation protein; FeMo cofactor biosynthesis protein nifB. PROBABLY INVOLVED IN THE SYNTHESIS OF THE FE-MO COFACTOR; High confidence in function and specificity. | 0.862 |
| azo0558 | nifD | azo0558 | azo0539 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogenase molybdenum-iron protein alpha chain (EC 1.18.6.1) (Nitrogenase component I) (Dinitrogenase). The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components: the iron protein and the molybdenum-iron protein; High confidence in function and specificity. | 0.818 |
| azo0558 | nifK | azo0558 | azo0540 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. | 0.840 |
| azo0558 | nifQ | azo0558 | azo0529 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership. | 0.820 |
| azo0558 | nifT | azo0558 | azo0541 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogen fixation protein [nifT],51% identity(72% Similarity) to SwissProt;P09427, TrEMBL;Q93JU8,57% identity. Has PF06988:NifT/FixU protein(IPR009727);This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in K. pneumoniae has only a limited effect on nitrogen fixation. No Signal peptide or TMH present; High confidence in function and specificity. | 0.855 |
| azo0558 | nifV | azo0558 | azo0551 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Homocitrate synthase is involved in the biosynthesis of the iron-molybdenum cofactor of nitrogenase and catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate into homocitrate. Similar to sprot|NIFV_AZOVI (51%) and to sprot|NIV1_ANASP (42%). Pfam (PF00682): HMG-CoA Lyase-like family InterPro (PS00815): Alpha-isopropylmalate and homocitrate synthase; High confidence in function and specificity; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.576 |
| azo0558 | nifW | azo0558 | azo0548 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogen fixation protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family. | 0.870 |
| azo0558 | nifX | azo0558 | azo0560 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Conserved hypothetical NifX protein. Homology to nifX of Azotobacter vinelandii of 47% (gi|128328|sp|P14887|NIFX_AZOVI(NBCI ENTREZ)). Pfam: Dinitrogenase iron-molybdenum cofactor. This family contains several NIF (B, Y and X) proteins which are involved in the synthesis of an iron-molybdenum cofactors (FeMo-co) in the dinitrogenase enzyme which catalyses the reduction of dinitrogen to ammonium. No signal peptide predicted. No TMHs; Conserved hypothetical protein. | 0.950 |
| azo0558 | nifZ | azo0558 | azo0547 | Conserved hypothetical protein(Has probable Nif-associated protein function)41% identity(62% similarity) to TrEMBL;Q9KJL5. Has PF03270(IPR004952):Protein of unknown function, DUF269;Members of this family may be involved in nitrogen fixation, since they are found within nitrogen fixation operons. NO Signal Peptide or TMH present; Family membership. | Nitrogen Fixation protein[nifZ], 51% identity (67% similarity) SwissProt;P14889,66% similarity to SwissProt;P23124. Has PF04319:NifZ domain;(IPR007415)This short protein is found in the nif (nitrogen fixation) operon. Its function is unknown but is probably involved in nitrogen fixation or regulating some component of this process. This 75 residue region is presumed to be a domain. It is found in isolation in some members and in the amino terminal half of the longer NifZ proteins. No Signal Peptide Or TMH reported Present; High confidence in function and specificity. | 0.894 |
| nifB | azo0549 | azo0523 | azo0549 | Nitrogen fixation protein; FeMo cofactor biosynthesis protein nifB. PROBABLY INVOLVED IN THE SYNTHESIS OF THE FE-MO COFACTOR; High confidence in function and specificity. | Conserved hypothetical protein. Homology to orf8 of Azotobacter vinelandii of 36% (tremble:Q44542). No domains predicted. No Signal peptide or TMH present. | 0.622 |
