Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
Score
azo0579Conserved hypothetical membrane protein. Homology to RSc2187 of R. solanacerarum of 44%. Tigrfam: 2A78: Carboxylate/Amino Acid/Amine Transporter Pfam: Intergral membrane protein DUF6 no signal peptide probable 6 TMHs; Conserved hypothetical protein. (318 aa)    
Predicted Functional Partners:
uppS
Probable undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
     
  0.603
emrY
Multidrug resistance protein B homolog. TRANSLOCASE THAT CONFERS RESISTANCE TO SUBSTANCES OF HIGH HYDROPHOBICITY (BY SIMILARITY). Presence of signal peptide and 14 transmembrane helices. Presence of DUF domains,CbiM, and bacterial cytochrome ubiquinol oxidase like domains efflux_EmrB: drug resistance transport; High confidence in function and specificity.
       0.559
azo0580
Putative methyl-accepting chemotaxis transducer,Chmtaxis_transd. Pfam: PF00015; MCPsignal. SMART: SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 1 transmembrane helices. Methyl-accepting chemotaxis serine transducer. CHEMOTACTIC-SIGNAL TRANSDUCERS RESPOND TO CHANGES IN THE CONCENTRATION OF ATTRACTANTS AND REPELLENTS IN THE ENVIRONMENT TRANSDUCE A SIGNAL FROM THE OUTSIDE TO THE INSIDE OF THE CELL AND FACILITATE SENSORY ADAPTATION THROUGH THE VARIATION OF THE LEVEL OF METHYLATION. ATTRACTANTS INCREASE THE LEVEL OF METHYLATION WHILE REPELLENTS DECREASE THE LEVEL OF METHYL [...]
       0.536
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
    
 0.485
ispB
Octaprenyl-diphosphate synthase; Polyprenyl synthetase,82% identity to TrEMBL;Q5P1Y1. Has Pfam;PF00348, Polyprenyl synthetase.(IPR000092,Polyprenyl_synt)A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of a variety of end products including cholesterol, dolichol, ubiquinone or coenzyme Q. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Among the enzymes that participate in that pathway, are a number of [...]
    
  0.459
ispA
Geranyltranstransferase; Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]. catalyzes the trans-addition of the three molecules of ipp onto dmapp to form geranylgeranyl pyrophosphate. InterPro: Polyprenyl synthetase; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family.
    
  0.459
azo2371
30S ribosomal protein S4, truncated. Homology of aa 1 to 108 with rpsD of N. europaea of 67% (sprot|RS4B_NITEU(SRS)). With S5 and S12 plays an important role in translational accuracy (By similarity). Pfam: Ribosomal protein S4/S9 n-terminal domain. no signal peptide. no TMHs; Family membership; Belongs to the universal ribosomal protein uS4 family.
     
  0.455
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
     
  0.455
azo1044
Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership.
    
  0.435
cbiQ
Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear.
    
  0.435
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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