| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0595 | dapF | azo0595 | azo0594 | 3',5'-cyclic-nucleotide phosphodiesterase; Conserved hypothetical protein. Coils2 Program reporting presence of 1 Coiled-Coil. Has SMART;SM00065,GAF domain;This domain is present in phytochromes and cGMP-specific phosphodiesterases. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyses the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. A phytochrome is a regulatory photoreceptor which exists in 2 forms that are reversibly interconvertible by light, the PR form that absorbs maximally in the red region of the spectrum, and the PFR form that absorbs maximally [...] | DapF protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.973 |
| azo0595 | xerC | azo0595 | azo0596 | 3',5'-cyclic-nucleotide phosphodiesterase; Conserved hypothetical protein. Coils2 Program reporting presence of 1 Coiled-Coil. Has SMART;SM00065,GAF domain;This domain is present in phytochromes and cGMP-specific phosphodiesterases. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyses the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. A phytochrome is a regulatory photoreceptor which exists in 2 forms that are reversibly interconvertible by light, the PR form that absorbs maximally in the red region of the spectrum, and the PFR form that absorbs maximally [...] | Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.861 |
| azo3724 | azo3725 | azo3724 | azo3725 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 0.994 |
| azo3724 | rnpA | azo3724 | azo3991 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.733 |
| azo3724 | ruvA | azo3724 | azo0602 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.742 |
| azo3724 | ruvB | azo3724 | azo0601 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.752 |
| azo3724 | ruvC | azo3724 | azo0571 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.732 |
| azo3724 | uvrB | azo3724 | azo1611 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.748 |
| azo3724 | xerC | azo3724 | azo0596 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.923 |
| azo3724 | xerD | azo3724 | azo3219 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.611 |
| azo3725 | azo3724 | azo3725 | azo3724 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 0.994 |
| azo3725 | rnpA | azo3725 | azo3991 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.733 |
| azo3725 | ruvA | azo3725 | azo0602 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.742 |
| azo3725 | ruvB | azo3725 | azo0601 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.785 |
| azo3725 | ruvC | azo3725 | azo0571 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.732 |
| azo3725 | uvrB | azo3725 | azo1611 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.748 |
| azo3725 | xerC | azo3725 | azo0596 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.811 |
| dapF | azo0595 | azo0594 | azo0595 | DapF protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 3',5'-cyclic-nucleotide phosphodiesterase; Conserved hypothetical protein. Coils2 Program reporting presence of 1 Coiled-Coil. Has SMART;SM00065,GAF domain;This domain is present in phytochromes and cGMP-specific phosphodiesterases. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyses the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. A phytochrome is a regulatory photoreceptor which exists in 2 forms that are reversibly interconvertible by light, the PR form that absorbs maximally in the red region of the spectrum, and the PFR form that absorbs maximally [...] | 0.973 |
| dapF | xerC | azo0594 | azo0596 | DapF protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.803 |
| rnpA | azo3724 | azo3991 | azo3724 | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 0.733 |
