STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0604Conserved hypothetical membrane protein. Homology to RS04896 of Ralstonia solanacearum o 43% (trembl|Q8Y1W8) Has PF06063, Domain of unknown function (DUF931);IPR010337;Family of transmembrane proteins with undetermined function. singal peptide. 2 THMs; Conserved hypothetical protein. (108 aa)    
Predicted Functional Partners:
azo0603
Conserved hypothetical membrane protein. Homology to BP3397 of B. pertussis of 41% (bpe:BP3397(KEGG)). Tigrfam: azlC: azlC protein (azlC). 6 TMHs no signal peptide; Conserved hypothetical protein.
 
  
 0.981
azo3634
Probable D-(-)-3-hydroxybutyrate oligomer hydrolase; Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB- oligomers) into 3HB-monomers; Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
  
     0.643
pilY1A
Putative type 4 pilus biogenesis protein; PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. Similar to trembl|Q8XW00 (31%). Pfam (PF01839): FG-GAP repeat SignalP reporting Signal peptide; Function unclear.
  
     0.593
ruvA
Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
 0.511
azo2461
Conserved hypothetical protein. Homology to mll6889 of M.loti. of 58% (trembl|Q987V8(SRS)). No domains predicted. No TMHs. No signal peptide.
  
     0.494
azo2591
Conserved hypothetical secreted protein. Homology to Daro03002418 of Dechloromonas aromatica of 58% (gi|53730135|ref|ZP_00150721.2|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.
  
     0.494
azo2160
Conserved hypothetical membrane protein. Homology to smc02385 of S. meliloti of 32% (trembl:Q92KI4). No domains predicted. Signal peptide. 6 TMHs; Conserved hypothetical protein.
  
     0.493
azo2178
probABLE TYPE 4 FIMBRIAL BIOGENESIS RELATEDTRANSMEMBRANE PROTEIN; Family membership.
  
     0.475
azo2277
Conserved hypothetical Na/H antiporter. Homology to Bucepa03004091 of B.cepacia of 41% (gi|46320868|ref|ZP_00221251.1|(NBCI ENTREZ)). Has PF00999 Sodium/hydrogen exchanger family; IPR006153. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserv [...]
  
     0.454
azo2397
Conserved hypothetical signaling protein.
  
     0.419
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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