STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0607Putative TonB-dependent receptor; Outer membrane TonB-dependent, hydroxamate-type ferrisiderophore receptor. Probably involved in iron transport. 30% TONB_C.IPR000531; TonB_receptor.IPR010105; TonB_siderophor. InterPro: TonB-dependent receptor protein Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide present; High confidence in function and specificity. (732 aa)    
Predicted Functional Partners:
ybiX
Putative PKHD-type hydroxylase protein, 69% Identity(82% simialrity) to SwissProt;P59727,Q8FJM69, (48% identity) Has SMART;SM00702, P4Hc,Prolyl 4-hydroxylase alpha subunit homologues: IPR006620; Pro_4_hyd_alph; Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor. Has PF03171,2OG-Fe(II) oxygenase superfamily;IPR005123;This family contains members of the 2-oxoglutarate [...]
 
  
 0.963
gox
Probable (S)-2-hydroxy-acid oxidase. Homology to gox of S. oleracea (spinach) of 42% (sprot|GOX_SPIOL). CATALYTIC ACTIVITY: (S)-2-hydroxy-acid + O(2) = 2-oxo acid + H(2)O(2). InterPro: FMN-dependent alpha-hydroxy acid dehydrogenases (IPR000262); Protein binding FMN and related compounds core region (IPR003009) Pfam: FMN-dependent dehydrogenase no signal peptide no TMHs guaA_Cterm: GMP synthase C-terminal d; Family membership.
  
    0.579
azo0605
Hypothetical protein. Homology to Daro03002672 of Dechloromonas aromatica of 51% (gi|41723577|ref|ZP_00150487.1|(NBCI ENTREZ)). Has PF04023, FeoA domain;IPR007167; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese. no signal peptide. no TMHs.
     
 0.512
feoB
Putative ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
     
 0.506
azo3555
TonB-dependent receptor, putative; COBALAMIN RECEPTOR PROTEIN; Specificity unclear.
  
   
 0.442
azo3966
Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. No TMHs.
  
     0.410
azo2400
Putative TonB outer membrane receptor protein.31% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; Function unclear.
  
   
 0.403
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.