STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exbB2Probable biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 50% ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: MotA/TolQ/ExbB proton channel family Pfam: MotA/TolQ/ExbB proton channel family no signal peptide no TMHs; Family membership. (253 aa)    
Predicted Functional Partners:
exbD3
Probable fiopolymer transport protein ExbD. Homology to exbD1 of X. campestris of 43%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; High confidence in function and specificity.
 
 
 0.983
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
 
 
 0.959
exbD5
Putative biopolymer transport protein exbD. Homology to exbD of E. coli of 34%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership.
 
 
 0.931
exbD1
Putative biopolymer transport protein ExbD. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton grandient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership.
 
 
 0.925
exbD2
Putative biopolymer transport protein ExbD. Homology to exbD2 of X. campestris of 36% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership.
 
 
 0.921
exbD6
Putative biopolymer transport protein. Homology to exbD1 of X. campestris of 31%. ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership.
 
 
 0.918
tolR
Putative translocation protein TolR. Holomology to tolR of P. aeruginosa of 30% (sprot|TOLR_PSEAE) Involved in eth TonB-independent uptake of proteins. no signal peptide probable 1 TMH; Family membership.
 
 
 0.910
exbD4
Putative biopolymer transport exbD2 protein. Homology to exbD2 of V. choloera of 31% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership.
 
 
 0.822
azo0235
Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.
 
 
 0.778
tonB2
Periplasmic biopolymer transport protein linking inner and outer membranes; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.777
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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