STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
bfr2Putative bacterioferritin; Iron-storage protein. (158 aa)    
Predicted Functional Partners:
bfd
Bacterioferritin-associated ferredoxin. Homology to psto4159 of P. syringae of 33% (trembl|Q87XL9). SEEMS TO ASSOCIATE WITH BFR; COULD BE A GENERAL REDOX AND/OR REGULATORY COMPONENT PARTICIPATING IN THE IRON STORAGE MOBILIZATION FUNCTIONS OF BFR. COULD PARTICIPATE IN THE RELEASE OR THE DELIVERY OF IRON FROM/TO BACTERIOFERRITIN (OR OTHER IRON COMPLEXES). Pfam: BFD-like [2Fe-2S] binding domain no signal peptide no TMHs; Conserved hypothetical protein.
 
 
 0.975
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.683
azo0409
Putative anti-sigma factor antagonists (STAS domain protein), STAS. Pfam: PF01740; STAS. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function; Function unclear.
   
  
 0.669
azo0618
Putative hemin uptake protein; 47% DUF1008. Pfam:PF06228; DUF1008; 1; High confidence in function and specificity.
       0.663
bfr3
Bacterioferritin (BFR) (Cytochrome B-1) (Cytochrome B-557). In E. coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central cavity of about 8 nm diameter.X-ray crystallographic studies have revealed a close structural similarity between BFR and the ferritins, a family of iron-storage proteins found in both eukaryota and prokaryota. Key role in iron homeostasis.InterPro: Bacterioferritin. Non-secretory protein bfr: bacterioferritin; High confidence in function and specificity.
  
  
  0.565
azo1789
Conserved hypothetical protein. Homology to bp0770 of B. pertussis of 37% (TrEMBL:Q7VZW1). no domains reported. no signal peptide. no TMHs.
   
  
 0.516
cyaY
Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
     
 0.481
azo2950
Multicopper oxidases are enzymes that possess three spectroscopically differentcopper centers. Similar to TREMBL:Q7X4G1 (71% identity); TREMBL:Q8U8U7 (71% identity); TREMBL:Q92ZC7 (70% identity). InterPro (IPR001117): Multicopper oxidase type 1. Pfam (PF00394): Multicopper oxidase. SignalP reporting signal peptide; Function unclear.
   
 
 0.444
azo0619
Conserved hypothetical protein; Similar to TREMBL:Q8Y2F3 (57% identity); TREMBL:Q7VVV4 (55% identity); TREMBL:Q9I111 (53% identity). Pfam (FAA_hydrolase): Fumarylacetoacetate (FAA) hydrolase family.
       0.437
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
     
 0.425
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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