STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
azo0620Conserved hypothetical secreted protein. Homology to an orf of G. sulfurreducens of 34% (tremblnew|AAR35905(SRS)). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein. (149 aa)    
Predicted Functional Partners:
pstC
Phosphate transport system permease protein probable; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
  
 0.971
azo1392
Phosphate transport system permease protein probable; Region start changed from 1521840 to 1521903 (-63 bases).
  
 0.967
azo0621
Conserved hypothetical secreted protein. Homology to ebA1833 of Azoarcus sp. EbN1 of 48% (gnl|keqq|eba:ebA1833(KEGG)). No domains predicted. Signal peptide Present. No TMH present; Conserved hypothetical protein.
 
    0.953
pstB
Phosphate transport ATP-binding protein probable; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
 0.949
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
    
 0.816
azo0409
Putative anti-sigma factor antagonists (STAS domain protein), STAS. Pfam: PF01740; STAS. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function; Function unclear.
  
  
  0.777
azo0622
Conserved hypothetical signaling protein. Homology to ebA1830 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA1830(KEGG)). Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. PF00672 HAMP. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. TMHMM reporting 2 transmembrane helices of which one is in the signal peptide. Signal peptide present; Conserved hypothetical protein.
       0.773
azo1571
Conserved hypothetical protein. Homology to hbpA of N. europaea of 56%. Protein consist of two domains: 1. bacterial extracellular sloute protein with homology to heme-binding protein A which is important for the heme aquisition and 2. a transmembrane helix a the C-terminus (unusual combination). Interpro: Bacterial extracellular solute-binding protein, family 5 (IPR000914) Pfam: Bacterial extracellular solute binding protein Signal peptide one TMH.
  
  
 0.769
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.768
ugpB
Glycerol-3-phosphate-binding periplasmic protein precursor. SN-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system ugpACE. 30% SBP_bac_1.IPR006061; SBP_dom1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present; High confidence in function and specificity.
     
 0.757
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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