STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0621Conserved hypothetical secreted protein. Homology to ebA1833 of Azoarcus sp. EbN1 of 48% (gnl|keqq|eba:ebA1833(KEGG)). No domains predicted. Signal peptide Present. No TMH present; Conserved hypothetical protein. (402 aa)    
Predicted Functional Partners:
azo0620
Conserved hypothetical secreted protein. Homology to an orf of G. sulfurreducens of 34% (tremblnew|AAR35905(SRS)). No domains predicted. Signal peptide. No TMHs; Conserved hypothetical protein.
 
    0.953
azo0622
Conserved hypothetical signaling protein. Homology to ebA1830 of Azoarcus sp. EbN1 of 63% (gnl|keqq|eba:ebA1830(KEGG)). Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF00563 EAL domain. PF00672 HAMP. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. TMHMM reporting 2 transmembrane helices of which one is in the signal peptide. Signal peptide present; Conserved hypothetical protein.
   
   0.795
vacJ
Putative surface lipoprotein. Homology to vacJ of S. flexneri of 26% (sprot|VACJ_SHIFL) Required for intercellular spreading. Pfam: VacJ like lipoprotein signal peptide no TMHs; Family membership.
    
 
 0.717
azo1485
Conserved hypothetical membrane protein. Homology ebA4071 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA4071(KEGG)). Has PF06930, Protein of unknown function (DUF1282); IPR009698; This family consists of several hypothetical proteins of around 200 residues in length. The function of this family is unknown although a number of family members are thought to be putative membrane proteins. no signal peptide. 5 TMHs; Conserved hypothetical protein.
  
     0.614
fimV2
Putative type 4 pilus biogenesis; In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear.
  
     0.576
tolB
Putative translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
    
 
 0.572
matA
Putative malonyl-CoA decarboxylase; Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. 40% Malonyl_CoA_deC. Pfam:PF05292; MCD; 1; High confidence in function and specificity.
       0.531
azo2858
Conserved hypothetical protein. Homology to CV2972 of C.violaceum of 51% (trembl:Q7NTT1). No domains predicted. No TMHs. No signal peptide.
  
     0.516
irgA2
Putative TonB-dependent receptor; 24% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; High confidence in function and specificity.
  
 
   0.513
azo0364
Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal p [...]
  
     0.500
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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