STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
matAPutative malonyl-CoA decarboxylase; Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. 40% Malonyl_CoA_deC. Pfam:PF05292; MCD; 1; High confidence in function and specificity. (460 aa)    
Predicted Functional Partners:
pta
Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein.
 
  
  0.906
accC1
Probable biotin carboxylase (a subunit of acetyl-coa carboxylase); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.893
accD
Probable acetyl-coenzyme A carboxylase carboxyl transferase subunit b; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
    
  0.891
fabD
Probable malonyl CoA-acyl carrier protein transacylase. Homology to fabD of E. coli of 54% (sprot|FABD_ECOLI). Is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein. InterPro: Acyl transferase domain (IPR001227); Manyl CoA-acyl carrier protein transaylase (IPR004410) Pfam: Acyl transferase domain Tigrfam: fabD: malonyl CoA-acyl carrier protein no signal peptide no TMHs; High confidence in function and specificity.
    
  0.891
dctQ1
DctQ1 protein; C4-dicarboxylate transport system,permease small protein,DctQ. The Dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 22% DctQ. Pfam:PF04290; DctQ; 1. TMHelix:4; High confidence in function and specificity.
 
 0.724
dctQ3
TRAP-type C4-dicarboxylate transport system, small permease component. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate.40% DctQ. Pfam:PF04290; DctQ; 1. TMHelix:3; Function unclear.
 
 0.708
azo3485
Conserved hypothetical iron-sulfur binding protein. Homology to pb1470 of B. pertussis of 48% (trembl|Q7VY84). Transfer of electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs; Family membership.
  
  
  0.692
dctQ4
TRAP-type C4-dicarboxylate transport system, small permease component. The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 22% DctM.IPR007387; DctQ.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF04290; DctQ; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1; Specificity unclear.
  
 0.654
azo2520
Conserved hypothetical membrane protein. Homology to PM1526 of Pasteurella multocida of 32% (trembl|Q9CKT0(SRS)). Pfam: PF04290;IPR007387;Tripartite ATP-independent periplasmic transporters, DctQ component; The function of the members of this family is unknown, but DctQ homologues are invariably found in the tripartite ATP-independent periplasmic transporters. No signal peptide. 4 TMHs; Conserved hypothetical protein.
  
 0.654
dctQ2
Putative TRAP-type C4-dicarboxylate transport system, small permease; The dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 45% DctQ. Pfam:PF04290; DctQ; 1. TMhelix:4; High confidence in function and specificity.
  
 0.647
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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