Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0638Conserved hypothtecial protein. Homology to Avin02002811 of Azotobacter vinelandii of 50% (gi|23103464|ref|ZP_00089946.1|(NBCI ENTREZ)). InterPro: Domain of unknown function DUF224 (IPR004017). no signal peptide. no TMHs. (465 aa)    
Predicted Functional Partners:
glcD1
Probable glycolate oxidase subunit glcD. Homology to glcD of E. coli of 64% (sprot|GLCD_ECOLI) InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; High confidence in function and specificity.
 
 0.943
dld
D-lactate dehydrogenase. Homology to dld of Mus musculus of 52% (trembl|Q8CIV4) CATALYZE THE STEREOSPECIFIC OXIDATION OF D-LACTATE TO PYRUVATE. InterPro: FAD linked oxidase C-terminal (IPR004113); FAD linked oxidase, N-terminal (IPR006093) Pfam: FAD binding damian; FAD linked oxidases, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership.
 
 
 0.931
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
 0.862
azo1167
Conserved hypothetical iron-sulfur protein. Homology to cv3028 of C. violaceum of 68% (trembl|Q7NTM6) Tigrfam: TIGR00273: iron-sulfur cluster binding protein Pfam: 4Fe-4S binding domain no TMHs no signal peptide; Conserved hypothetical protein.
 
 
 0.779
glpA
Putative glycerol-3-phosphate dehydrogenase. Homology to glpA of B. hermsir of 38% (trembl|Q84I21) FAD-dependent glycerol-3-phosphate dehydrogenase catalyzes the conversion of glycerol-3-phosphate into dihydroxyacetone phosphate: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. InterPro: D-amino acid oxidase (IPR000927) Pfam: FAD dependent oxidoreductase no signal peptide no TMHs gidA: glucose-inhibited division prot; Family membership.
  
 
 0.775
glcD2
Putative glycolate oxidase subunit GlcD. Homology to glcD of E. coli of 32% (sprot|GLCD_ECOLI). InterPro: FAD linked oxidase C-terminal (IPR004113);m FAD linked oxidas, N-terminal (IPR006093) Pfam: FAD binding domain; FAD linked oxidase, C-terminal domain Tigrfam: glcD: glycolate oxidase subunit GlcD no signal peptide no TMHs; Family membership.
 
 
 0.761
azo3485
Conserved hypothetical iron-sulfur binding protein. Homology to pb1470 of B. pertussis of 48% (trembl|Q7VY84). Transfer of electrons in a wide variety of metabolic reactions. InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain (IPR001450). Pfam: 4Fe-4S binding domain. no signal peptide. no TMHs; Family membership.
    
 0.708
azo1168
Conserved hypothetical protein. Homology to DVU1781 of D.vulgaris of 45% (tremble:Q72B57). Has PF02589 DUF162 domain:Uncharacterized ACR, YkgG family. No signal peptide or TMH reported present.
 
 
 0.664
azo2436
Conserved hypothetical protein. Homology to orf4 of P. putida of 59% (trembl|Q93JW8). Pfam: DUF336. This family contains uncharacterised sequences, including several GlcG proteins. The alignment contains many conserved motifs that are suggestive of cofactor binding and enzymatic activity. no signal peptide. no TMHs.
 
  
 0.662
icmF
Probable methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.655
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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