STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aggAPutative outer membrane efflux protein. Homology to aggA from P. putida of 35%. The OEP family (outer membrane efflux protein) allow export of a variety of substrates in Gram negative bacteria. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Function unclear. (480 aa)    
Predicted Functional Partners:
hylD
Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership.
 
 0.956
macB
ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.939
azo0646
Toxin secretion ABC transporter permease and ATP-binding protein; HlyB-family protein. Similar to TREMBL:Q7WBM7 (50% identity); TREMBL:Q9KKL9 (41% identity); SWISSPROT:P18770 (28% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting four transmembrane helices. TC (3.A.1.109.3): LapA adhesin protein exporter, LapB; High confidence in function and specificity.
 
 
 0.903
azo0653
Conserved hypothetical secreted protein. Homology to BB1185 of Bordetella bronchiseptica of 49% (trembl|Q7WN55(SRS)) Signal peptide present. No TMHs Has PF06035, Bacterial protein of unknown function (DUF920);IPR010319; This family consists of several hypothetical bacterial proteins of unknown function; Conserved hypothetical protein.
 
   
 0.891
azo0652
Conserved hypothetical GGDF domain protein. Homology to CV0310 of Chromobacterium violaceum of 34% (trembl|Q7P1A3). Has IPR003660_HAMP,SMART;SM00304:This domain is known as the HAMP domain for histidine kinases,adenylyl cyclases, methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160_GGDEF(SMART;SM00267);This domain is found linked to a wide range of non-homologous domains in [...]
 
  
 0.867
cusB
Cation efflux transmembrane protein; Putative membrane fusion protein silB precursor. COMPONENT OF THE SIL CATION-EFFLUX SYSTEM THAT CONFERS RESISTANCE TO SILVER. MAY BE PART OF A THREE-COMPONENT CATION/PROTON ANTIPORTER; High confidence in function and specificity.
  
 0.866
tolB
Putative translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 0.857
azo0835
Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership.
 
 0.838
azo0651
Conserved hypothetical protein. Homology to ebB52 Azoarcus sp. EbN1 of 40% (gnl|keqq|eba:ebB52(KEGG)). No domains predicted. No TMHs. No signal peptide.
  
     0.757
ompA2
Putative outer membrane protein, OmpA family,36% identity(51%similarity) to TrEMBL;Q93IS0.TrEMBL;Q7AXY6(36% identity) TMHMM2 reporting presence of 1 TMH's. Has PF00691, OmpA family;IPR006665, OmpA/MotB:Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins (such as ompA) MEDLINE:,but some are small lipid-anchored proteins.It is also found in MotB and related proteins. They are present in the outer membrane of many Gram-negative organisms; Conserved hypothetical protein.
   
 0.757
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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