STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
azo0665Conserved hypothetical protein; Entry name:- Q9I0U5 Primary accession number:-Q9I0U5 InterPro:- IPR008934; AcPase_VanPerase. IPR000340; DS_phosphatase. IPR000326; PA_PTPase. Number of predicted TMHs: 8 Prediction: Non-secretory protein Signal peptide probability: 0.061 IPR000387; TYR_phosphatase. Pfam PF00782; DSPc; 1. PF01569; PAP2; 1. Identity:- 58%. (452 aa)    
Predicted Functional Partners:
azo0663
Probable CDP-alcohol phosphatidyltransferase family protein; Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. Entry name Q8PQ18 Primary accession number: Q8PQ18 InterPro IPR000462; CDP-OH_P_trans. Pfam PF01066; CDP-OH_P_transf; 1. Identities = 114/203 (56%),Prediction: Signal peptide Signal peptide probability: 0.988 Number of predicted TMHs: 3; Family membership.
 
 0.974
azo0668
Conserved hypothetical phoshpatidate cytidyltransferase. Homology to pa2536 of P. aeruginosa (trembl|Q9I0U8). Phosphatidate cytidylyltransferase is the enzyme that catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate (PA): CTP + phosphatidate = diphosphate + CDP-diacylglycerol Pfam: Phospatidate cytidyltransferase signal peptide 7 TMHs InterPro: Phosphatidate cytidylyltransferase stp: serine transporter; Family membership.
 
 
  0.969
azo0664
Conserved hypothetical protein; Similar to TREMBL:Q87TY0 (64% identity); TREMBL:Q8PQ17 (61% identity); SWISSPROT:P76092 (55% identity).
 
    0.967
azo0667
Putative acyltransferase; FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-acyl carrier protein as the fatty acyl donor. CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name:-SWISSPROT:PLSC_ECOLI Prim. accession # P26647 InterPro:-IPR002123; Acyltransferase. IPR004552; AGP_acyltrn. Pfam:-PF01553; Acyltransferase; 1. Identities = 42/127 (33%) Prediction: Non-secretory protein Signal peptide probability: 0. [...]
 
 
  0.953
azo1211
Conserved hypothetical protein. Homology bll7767 of B. japonicum of 30% (trembl|Q89CN0) Pfam: WD domain, G-beta repeat no signal peptide no TMHs.
   
 0.885
azo0666
Conserved hypothetical membrane protein. Homology to PA2538 of Pseudomonas aeruginosa of 36% (trembl|Q9I0U6). No domains predicted. No signal peptide. 3 TMHs; Conserved hypothetical protein.
       0.773
azo3617
Putative calcium binding protein,40% similarity to TrEMBL;O22845. Has 3 EFh|EF-hand, calcium binding motif;(SMART|SM00054):Many calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand. This type of domain consists of a twelve residue loop flanked on both side by a twelve residue alpha-helical domain. In an EF-hand loop the calcium ion is coordinated in a pentagonal bipyramidal configuration. The six residues involved in the binding are in positions 1, 3, 5, 7, 9 and 12; these residues are denoted by X, Y, Z, -Y, -X [...]
    
 0.731
inaA
Conserved hypothetical InaA protein. Homology to inaA of P. putida of 39% (gnl|keqq|ppu:PP0904(KEGG)). Pfam: Lipopolysaccharide kinase (Kdo/WaaP) family. These lipopolysaccharide kinases are related to protein kinases Pkinase. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. It has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. e [...]
    
 0.723
waaP3
Lipopolysaccharide core biosynthesis protein. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.
    
 0.723
azo3571
Conserved hypothetical protein; InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster.
    
 0.723
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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