STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nodDProbable nodulation protein,; Function unclear; Belongs to the LysR transcriptional regulatory family. (317 aa)    
Predicted Functional Partners:
urtE
ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains. Similar to trembl|Q88DI0 (59%) and to sprot|BRAG_PSEAE (35%). Pfam: ABC transporter Smart: AAA ATPases; Specificity unclear.
       0.661
lysR
Putative transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.487
azo2367
Transcriptional regulator, LysR family,; Function unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.487
bdhR
Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.467
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.462
gstR1
Putative transcriptional regulator. Homology to gstR of R. leguminosarum of 37% (tremble:Q52827). Has PF00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family.IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC,iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR,nodD, [...]
  
     0.440
azo1015
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.438
azo2567
Putative LysR-family transcriptional regulator protein.62% identity to TrEMBL;Q63NK9,Q8XQV8,Q62B59,Q8VL17. PF00126, Bacterial regulatory helix-turn-helix protein, lysR family;IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse,but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB,lysR, metR, mkaC, mleR, nahR, nhaR, nodD, n [...]
  
     0.435
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.423
azo1161
Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 29% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear.
  
     0.422
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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