STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
creDInner membrane protein CreD; CreD confers tolerance to colicin E2. Similar to SWISSPROT:P08369 (35% identity). TMHMM reporting six transmembrane helices; High confidence in function and specificity. (443 aa)    
Predicted Functional Partners:
creC
Catabolite repression sensor kinase for PhoB; Sensor protein creC,; High confidence in function and specificity.
 
   
 0.894
nagZ1
Putative beta-hexosaminidase; (N-acetyl-beta-glucosaminidase)(Beta-N- acetylhexosaminidase). Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity). Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D-glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta-GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. May play a role in signal transduction between host and organism. 34% Glyco_hydro_3N. Pfam:PF00933; Glyco_hydro_3; 1. TMhelix:2; High confidence in function and specificity.
 
   
 0.819
azo0074
Hypothetical protein yfbK. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders [1]. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. trembl:Q8P6Q2: 55% identity; 66% similarity InterPro:IPR002016; Peroxidase. IPR002035; VWF_A. Pfam: PF00092; VWA; 1. SMART: SM00327; VWA; 1. cdhD: CO dehydrogenase/acetyl-CoA syn Signal peptide present (0.927 probability); SignalP predicted. No transmembrane helices (TMHMM predicted); Function unclear.
  
     0.607
creB
Transcriptional regulatory protein creB,Response_reg. IPR001867; Trans_reg_C. Pfam:PF00072; response_reg. PF00486; trans_reg_C. SMART:SM00448; REC. Transcriptional regulatory protein creB. MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM CREC/CREB INVOLVED IN CATABOLIC REGULATION; High confidence in function and specificity.
 
     0.590
azo0147
Conserved hypothetical membrane protein. Homology to RS05051 of Ralstonia solanacearum of 45% (trembl|Q8Y1A4(SRS)). TMHMM2 reporting the presence of 26 TMH's. Signal P reporting Signal Peptide present. Coils2 program reporting presence of Coiled coil; Conserved hypothetical protein.
  
     0.568
azo0700
Hypothetical protein, 52% identity to TrEMBL;Q8XYG9. Has PF03781, Domain of unknown function (DUF323);IPR005532; This presumed domain is found in bacterial proteins. In some cases these proteins also contain a protein kinase domain. The function of this domain is unknown. The domain has also been found in a eukaryotic protein, required for post-translational sulphatase modification; Function unclear.
       0.513
mgtE
Putative magnesium transport protein; Acts as a magnesium transporter.
       0.458
azo3078
Putative transcriptional regulator, deoR-family.
  
     0.455
azo3079
Conserved hypothetical protein. Homology to stm0409 of S. typhimurium of 46% (tremble:Q7CR38). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. Pfam: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. no signal peptide. no TMHs.
  
     0.429
rtcB
rtcB protein, 57% identical(70% similairty) to TrEMBL;Q7NZ85 TrEMBL;Q8FCS7(56% identity). Has IPR001233;UPF0027(PF01139, Uncharacterized protein family):A number of uncharacterized proteins including Escherichia coli rtcB, Mycobacterium tuberculosis MtCY441.01., Caenorhabditis elegans F16A11.2 and Methanococcus jannaschii MJ0682 belong to this family. Has no Signal peptide or TMH present; High confidence in function and specificity.
  
     0.428
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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