STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0708Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein. (300 aa)    
Predicted Functional Partners:
exbB3
Conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership.
 
 
 0.900
aroE
AroE protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.796
mtgA
Probable monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
       0.792
exbD4
Putative biopolymer transport exbD2 protein. Homology to exbD2 of V. choloera of 31% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership.
 
 
 0.787
azo0709
Putative exoribonuclease II (EC: 3.1.13.1), RNase R.
       0.740
azo3555
TonB-dependent receptor, putative; COBALAMIN RECEPTOR PROTEIN; Specificity unclear.
 
 
 
 0.701
fhuA1
In E.coli this receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin. Signal peptide; Specificity unclear.
  
 
 0.692
azo2217
Putative TonB-dependent receptor; Similar to FecA, ferric-citrate outer membrane receptor in E.coli, involved in the recognition and internalization of ferric-citrate. InterPro: TonB-dependent receptor protein; Function unclear.
  
 
 0.692
fyuA
Putative TonB-dependent receptor; Yersinia enterocolitica,iron-repressible outer membrane protein, FyuA. FyuA:RECEPTOR FOR THE BACTERIOCIN PESTICIN AND FOR THE SIDEROPHORE YERSINIABACTIN. TonB-dependent outer membrane receptor; Function unclear.
  
 
 0.692
fecA
Ferric-citrate outer membrane receptor,FecA.Involved in the recognition and internalization of ferric-citrate in E.coli. SPECIFIC RECEPTOR FOR THE SIDEROPHORE FERRIC PSEUDOBACTIN 358. InterPro: TonB-dependent receptor protein; High confidence in function and specificity.
  
 
 0.692
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.