| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0723 | azo0983 | azo0723 | azo0983 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.612 |
| azo0723 | azo2527 | azo0723 | azo2527 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership. | 0.584 |
| azo0723 | azo3595 | azo0723 | azo3595 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | Hypothetical protein predicted by Glimmer/Critica. | 0.678 |
| azo0723 | bioC2 | azo0723 | azo2818 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | Putative biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.619 |
| azo0723 | dsbC | azo0723 | azo0724 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | Putative protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.785 |
| azo0723 | nagAa | azo0723 | azo2517 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity. | 0.658 |
| azo0723 | ubiA | azo0723 | azo0479 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.706 |
| azo0723 | ubiG | azo0723 | azo2589 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.982 |
| azo0723 | ubiX | azo0723 | azo3814 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.929 |
| azo0723 | yigC | azo0723 | azo3658 | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 3-polyprenyl-4-hydroxybenzoate decarboxylase and related dec; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.930 |
| azo0983 | azo0723 | azo0983 | azo0723 | Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; Belongs to the glutaredoxin family. Monothiol subfamily. | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 0.612 |
| azo0983 | ubiG | azo0983 | azo2589 | Conserved hypothetical protein. Homology to ne1911 of N. europaea of 67%. InterPro: Glutaredoxin-related protein (IPR004480) TIGR00365: glutaredoxin-related protein no signal peptide no TMHs; Belongs to the glutaredoxin family. Monothiol subfamily. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.478 |
| azo2527 | azo0723 | azo2527 | azo0723 | Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership. | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 0.584 |
| azo2527 | azo3595 | azo2527 | azo3595 | Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership. | Hypothetical protein predicted by Glimmer/Critica. | 0.625 |
| azo2527 | bioC2 | azo2527 | azo2818 | Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership. | Putative biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.592 |
| azo2527 | nagAa | azo2527 | azo2517 | Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership. | Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity. | 0.838 |
| azo3595 | azo0723 | azo3595 | azo0723 | Hypothetical protein predicted by Glimmer/Critica. | Putative monoxygenase. Pfam: Monoxygenase InterPro: Aromatic-ring hydroxylase (flavoprotein monoxygenase); High confidence in function and specificity. | 0.678 |
| azo3595 | azo2527 | azo3595 | azo2527 | Hypothetical protein predicted by Glimmer/Critica. | Cytochrome P450s are involved in the oxidative degradation of various compounds. Particularly well known for their role in the degradation of environmental toxins and mutagens. Similar to SWISSPROT:P77902 (30% identity); TREMBL:Q59910 (32% identity); SWISSPROT:O34374 (28% identity). Pfam (PF00067): Cytochrome P450; Family membership. | 0.625 |
| azo3595 | ubiA | azo3595 | azo0479 | Hypothetical protein predicted by Glimmer/Critica. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.674 |
| azo3595 | ubiX | azo3595 | azo3814 | Hypothetical protein predicted by Glimmer/Critica. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.484 |