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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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bafProbable Bvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (263 aa)    
Predicted Functional Partners:
birA
biotin--[acetyl-CoA-carboxylase] ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. birA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-coa:carbon- dioxide ligase. this protein also activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins. InterPro: Biotin--acetyl-CoA-carboxylase ligase birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear.
 
    0.995
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.983
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.945
dfp
Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.905
coaE
CoaE protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.865
azo2378
Hypothetical protein, 38% identity (50% similarity) to TrEMBL;Q87X35 Has PF04336, Protein of unknown function,DUF479;IPR007431,This family includes several bacterial proteins of uncharacterised function; Function unclear.
     
  0.855
azo0732
Conserved hypothetical secreted protein. Homology to rs03277 of R. solanacearum of 30% (TrEMBL:Q8Y2M5). No domains predicted. signal peptide. no TMHs; Conserved hypothetical protein.
       0.799
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.651
yacG
Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
       0.588
yacF
Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
       0.581
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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