STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrBNitrogen regulation protein NR(II),; High confidence in function and specificity. (357 aa)    
Predicted Functional Partners:
ntrC
Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.995
glnB
PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ2 (100%) and to trembl|Q8XWX5 (82%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity.
  
 0.988
azo3381
Hypothetical signaling protein.
  
 0.936
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
 
 
0.902
glnY
PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ4 (100%) and to trembl|Q9RBK0 (78%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity.
  
 0.899
glnK
PII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ3 (100%) and to trembl|Q7NQY3 (87%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity.
  
 0.899
fleR
Sigma-54 dependent response regulator,; High confidence in function and specificity.
 0.868
azo2450
Putative two-component system sensor protein,; Function unclear.
 
 
0.858
vsrB
Putative virulence regulator protein,ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR003660; HAMP. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00672; HAMP. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00304; HAMP. SM00448; REC. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices; Specificity unclear.
 
 0.857
azo2362
Putative sensor kinase/response regulator hybrid protein,; Specificity unclear.
 
 0.844
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.